Previously, the CD8 effector memory T (TEM) cells have been identified as a potential biomarker of acute rejection in patient awaiting for a lung transplantation(1). The aim of the study was to correlate CD8 TEM with severity of acute rejection after LT. Material and Methods 76 patie...
Although the generation of CD8+memory T cells is a defining feature of adaptive immune responses, how exactly memory T cells develop during primary immune responses has remained a controversial subject. Proposed models include a conventional linear differentiation pathway, whereby naive T cells go throu...
The CD8+ memory T cell population is heterogeneous, and it is unclear which subset(s) optimally mediate the central goal of the immune system—protection against infection. Here we investigate the protective capacities of CD8+ T cell subsets present at the memory stage of the immune response. ...
A subsequent flow cytometric analysis of paired blood and endocervix-derived cells (n=16) revealed that while all the CD8 T cell subsets: naïve, effector memory (TEM), central memory (TCM) and terminally differentiated effector memory (TEMRA) can be found in the blood, the endocervix is ...
Preferential Cell Death of CD8+ Effector Memory (CCR7CD45RA) T Cells by Hydrogen Peroxide-Induced Oxidative Stress 1 R. Norell et al., "Preferential cell death of CD8+ effector memory (CCR7 - CD45RA-) T cells by hydrogen peroxide-induced oxidative stress," The ... A Takahashi,MGV Hanso...
As effector memory T cells (Tem) are the predominant population elicited by chronic parasitic infections, increasing our knowledge of their function, survival and derivation, as phenotypically and functionally distinct from central memory and effector T cells will be critical to vaccinedevelopment for th...
(ɪˈfɛk tər) n. 1.Also,effecter.a person or thing that effects something. 2. a.an organ, cell, etc., that reacts to a nerve impulse, as a muscle by contracting or a gland by secreting. b.the part of a nerve that conveys such an impulse. ...
CD8+ T cells central memory stemness T cell factor 1 (Tcf1) (Tcf7) effector differentiation Granzyme LCMV infection vaccination Introduction Infection activates very rare antigen-specific naive CD8+ T cells (Tn), which expand and differentiate into cytotoxic effector cells (Teff) that clear pathoge...
Besides, we previously revealed that effector/memory (EM) CD8 + T cell proportion significantly elevates in peripheral of patients with MS [19]. These CD8 + TEM cells synergizing with macrophages are capable of mediating autoimmune peripheral neuropathy, which shares similar pathogenesis...
In the present study, we initially reported that the percentages of CD4+ and CD8 effector memory T cells (Tem cells) were increased in PB and BM of AA. The... X Hu,G Yan,Y Wang,... - 《Haematologica》 被引量: 33发表: 2009年 加载更多0关于...