Results generated using a compaction simulator as well as a number of rotary tablet presses are presented for a range of pharmaceutical excipients and placebo formulations. As a result of combined interactions between the material behaviour during compaction, powder-die wall friction and process ...
Nano-graphene lubricating oil with appropriate concentration shows excellent performance in reducing friction and wear under different working conditions of diesel engines, and has been widely concerned. Lubricating oil has a significant impact on particulate matter (PM) emissions. At present, there are ...
The compression characteristics of the materials in terms of porosity-pressure displacement profiles and surface area-pressure profiles as well as the tablet strength by diametral compression were evaluated. The results showed that water absorbed at particle surfaces has a very limited effect on the ...
The compression during tabletting is a complex and irreversible dynamic process and the study of it with instrumented tablet presses is beneficial for process and formulation optimization. The compaction and ejection cycle provides us suitable signals about the tabletting process. Instrumented presses used...
TABLET COMPACTIONMECHANICAL-BEHAVIORFRICTIONThis paper investigates the compaction of pharmaceutical powders using different shapes of punches. We introduce a model of mechanical behaviour Drucker-Prager Cap (DPC), using the approach of compressible continuous media. The model parameters that are depending ...
The API: IM ratio (X1) and compression force (X2) were selected as independent variables. The dependent variables were as follows: the parameters of the tabletting process - lubrication coefficient (R-value), relative elasticity, friction work - and characteristics of the dosage form such as ...
The obvious peak might be a result of particle formation due to combustion initiated by friction between sandpaper and wood. Combustion as a side effect of abrasion produces particles <50 nm scale [38,39,40]. These particles might be volatile organic compounds, semi-volatile organic compounds, ...
processes Article The Effect of Very Cohesive Ultra-Fine Particles in Mixtures on Compression, Consolidation, and Fluidization Abbas Kamranian Marnani 1,* , Andreas Bück 2, Sergiy Antonyuk 3 , Berend van Wachem 1, Dominique Thévenin 4 and Jürgen Tomas 1,† 1 Institute of Mechanical ...
This was done to study the impact of granule size range on the tablet tensile strength. The granules were not pre-lubricated internally or externally, however, the punch and die of the compression machine were coated with a thin layer of magnesium stearate to minimise sticking and picking. ...