三观震碎之:今天Zhao老师说一个变量既有可能是修饰效应Effect modification也有可能是混杂confounding 比如: 研究vitamin D 和得新冠的关系 年龄是confounding的理解:年龄可以影响VD摄入,也可以影响是否得新冠。 年龄是Effect modification的理解:年龄会影响机体对于VD 的吸收和利用,导致不同年龄层的效应不同。 然后,没有...
@Yannan Tang，分别从定义和统计方法上面总结了混杂(confounding)和效应修饰作用(effect modification)的不...
Effect modification描述的是，在不同因素M存在的情况下，暴露E对结果O的关系在量或性质上存在差异。这通常涉及潜在的生理病理机制的差异。在实际操作中，需要首先确认E与M之间是否存在交互作用。如果有交互作用，需要对E进行分层处理。区分confounding 和effect modification的关键在于具体情境的分析。例如，在...
In this review, we discuss the importance of confounding and effect modification in pediatric/congenital interventional cardiology research. We define these terms and discuss strategies (both in study design and data analysis) to mitigate error introduced by confounding and effect modification. The ...
Lecture_6_effect_modification Effectmodification/interaction Interactionoreffectmodification Two ormoreriskfactorsmodifytheeffectofeachotherwithregardtotheoccurrenceorlevelofagivenoutcomeAlsoknownaseffectmodificationSynergistic(positiveinteraction)–potentiatestheeffectoftheexposureofinterestAntagonistic(...
Which of the following techniques can be used to control for confounding in the analysis stage of a study? a. randomization b. stratification c. effect modification d. blinding What is the purpose of experimental control? What variables sho...
N. Experimental study on modification of water-based filtercake to improve the bonding strength at the wellbore cement-formation interface. Pet. Res. 8 (4), 531–540. https://doi.org/10.1016/j.ptlrs.2022.10.002 (2023). Article CAS Google Scholar Das, S. et al. A holistic approach ...
We examined effect modification by age, sex, weight status (obese vs nonobese), amount of MVPA, and chronic disease, using likelihood ratio tests to compare models with and without an interaction term. Further stratified analyses were conducted to compare the models of each subsample. To ...
Which of the following techniques can be used to control for confounding in the analysis stage of a study? a. randomization b. stratification c. effect modification d. blinding What are the dependent and independent variables in an experiment?
Thus, this review aims to provide an up-to-date overview of our current understanding of the impact of exercise on fertility, with particular consideration of patient characteristics that may warrant a modification of one’s specific recommendations. Materials and methods An electronic search of Ovid...