Regulation of OPA1-mediated mitochondrial fusion by leucine zipper/EF-hand-containing transmembrane protein-1 plays a role in apoptosis. Cell Signal. 2009; 21:767-777.Piao L, Li Y, Kim SJ, Sohn KC, Yang KJ, Park KA et al. Regulation of OPA1-mediated mitochondrial fusion by leucine ...
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Secondary structure prediction of AIF-1 reveals disordered regions and one functional EF-hand. Swiprosin-1/EFhd2 and Swiprosin-2/EFhd1 exhibit a disordered region at the N-terminus, followed by two EF-hands and a coiled-coil domain. Whereas both proteins are similar in their predicted ...
Leucine zipper-EF-hand-containing transmembrane protein1 (LETM1) is located in the mitochondrial inner membrane and is defective in Wolf-Hirschhorn syndrome. LETM1 contains only one transmembrane helix, but it behaves as a putative transporter. Our data shows that LETM1 knockdown or overexpression ...
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We show expression of exogenous CaV2α1 in the neurites of culturedAplysiaSN. One proposed mechanism for heterosynaptic depression inAplysiais through inhibition of CaV2. Here, we demonstrate that heterosynaptic depression of the CaV2 calcium current is inhibited when a channel with a Y-F ...
Most recent evidence points to the C-terminus of the α1C subunit, with its EF-hand binding motif, as being critical in this process. The EF-hand binding motif is mostly conserved between the C-termini of six of the seven α1 subunit Ca2+ channel genes. The role of E1537 in the C...
In 2002, sperm-specific phospholipase C zeta1 (PLCZ1) was discovered and through these 20 years, it has been established as the predominant sperm oocyte-ac... A Thanassoulas,K Swann,FA Lai,... - 《Reproduction the Official Journal of the Society for the Study of Fertility》 被引量:...