A transposon element carrying a reporter gene (usually beta-galactosidase), linked to a very weak promoter, is induced to ‘jump’ within the genome. If the P-element re-inserts within the sphere of influence of promoters and enhancers of some (random) gene, then the reporter gene is also...
APOE/FAD-Tg models express h-apoE under heterologous promoters that may be activated by stressors [glial fibrillary acidic protein (GFAP) (27, 30)], or by cell types that are not the primary producers of apoE [neuron-specific enolase (31)], rather than the endogenous m-apoE promoter. Cur...
脊椎动物 RNA聚合酶I 的启动子有两部分组成,包括转录起点附近的核心启动子 (core promoter) ,和起点 5'上游 100bp 左右的上游控制元件 (upstream control element,UCE) 。核心启动子从 -45 到 +20,负责转 录的起始。 UCE 从-180 延伸到 -107,此区可增加核心元件的转录起始的效率。 RNA Pol I需要2种辅助...
EFNA1, EFNA3, and EFNA4 had similar mutation patterns. Thereafter, we performed a correlation analysis between EFNA expression and DNA methylation to explore the effect of promoter region DNA methylation on EFNA expression (Fig.3C). The mRNA expression of ...
这些作者重点研究了二价启动子(bivalent promoter),其定义为同时存在激活性(H3K4me3)和抑制性(H3K27me3)组蛋白标记,并且通常由多梳抑制复合物1和2(PRC1和PRC2)占据。在干细胞或祖细胞中,二价启动子被认为将发育调节因子维持在“蓄势待发的状态”,准备在...
[16]RAMI RE C, SCHOLT S C, DIAZ O, et al. Transactivation of the hepatitis B virus core promoter by the nuclear receptor FXRalpha[J]. J Virol, 2008, 82(21): 10832-10840. [17]KIM BK, LIM SO, PARK YG. Requ...
By ANTHONY McCARTNEY
RNA聚合酶－催化转录的酶顺式作用元件cis-actingelement－与结构基因串联的特定DNA序列反式作用因子trans-actingfactor－可调节转录的一类蛋白质 基因概念：结构基因、转录起始、终止和调节有关的DNA序列。原核生物中，相关的一组基因连在一起构成操纵子，由单个启动子来调节整个操纵子的转录真核...
LIU H-成牙本质细胞相关基因启动子研究和应用进展 学号 200532220003 密级 武汉大学本科文献综述 成牙本质细胞相关基因启动子的研究和应用进展 院（系）名称：口腔医学院 专业名称：口腔医学八年制 学生姓名：刘欢 指导教师：陈智教授 二○一○年十一月
Association of the serotonin transporter gene promoter region (5-HTTLPR) polymorphism with biased attention for emotional stimuli. J Abnorm Psychol, 2009, 118: 670–681 3740 https://engine.scichina.com/doi/10.1360/N972017-00832 评述 108 Hysek C M, Schmid Y, Simmler L D, et al. MDMA ...