AptamersiRNAEukaryotic elongation factor 1A1 proteinChronic lymphocytic leukemiaBackground: The effectiveness of therapies for chronic lymphocytic leukemia (CLL), the most common leukemia in Western countries adults, can be improved via a deeper understanding of its molecular abnormalities. Whereas the ...
Human T-cell leukemia virus type-I oncoprotein tax inhibits Fas-mediated apoptosis by inducing cellular FLIP through activation of NF-kappaB. Genes Cells 2006; 11: 177–191. 38. Iwano T, Tachibana M, Reth M, Shinkai Y. Importance of TRF1 for functional telomere structure. J Biol Chem 2003...
E. et al. Targeting PBR by hexaminolevulinate-mediated photodynamic therapy induces apoptosis through translocation of apoptosis-inducing factor in human leukemia cells. Cancer Res. 65, 11051–11060 (2005). 20. Zawacka-Pankau, J. et al. Tumor suppressor Fhit protein interacts with protoporphyrin ...
团队主要依托陕西省生物技术与生化工程重点实验室开展研究工作,现拥有国家级人才项目获得者1人,省部级人才项目获得者3人。 近五年,团队成员以第一作者或通讯作者在Nat Methods, Nat Chem Biol, Nat Commun, Leukemia, J Extracell Vesicles, Chem Co...
在Leukemia, CCR 等杂志作为主要通讯作者发表多篇SCI论著,主持3项国自然面上基金及多项省级基金 成人T淋巴母细胞淋巴瘤的精准治疗 T-LBL虽然发病较为罕见,但是复发率较高,可达到40%-60%。T-LBL患者复发后缺乏有效的治疗手段,病死率...
The STAT5 inhibitor pimozide decreases survival of chronic myelogenous leukemia cells resistant to kinase inhibitors The transcription factor STAT5 is an essential mediator of the pathogenesis of chronic myelogenous leukemia (CML). In CML, the BCR/ABL fusion kinase causes... EA Nelson,SR Walker,E ...
In the following cytochemistry stainings,which one is the most important in clinical to diagnose acute leukemia A. POX B. Ferric staining C. PAS D. NAP E. None of above 查看完整题目与答案 关于包合物的阐述错误的为( ) A. 包合物是一种药物被包裹在高分子材料中形成的囊状物 ...
The surface engagement of high affinity immunoglobulin E receptor (Fc epsilon RI) of rat basophilic leukemia 2H3 (RBL-2H3) cells induced histamine secretio... YANO,H. - 《J.biol.chem》 被引量: 1887发表: 1993年 Reproducibility and comparison of responses to inhaled histamine and methacholine....
浆细胞白血病(Plasmacellleukemia,PCL)是骨髓瘤细胞细胞侵犯外周血且达到一定比例的状态,最早是1904年由意大利学者报道的,但诊断标准却是很多年以后才有的。 1974年,美国梅奥诊所(MayoClinic,其官方中文名是“妙佑医疗国际”)的学者提出了PCL的诊断标准:外周血中肿瘤性浆细胞>2...
参考文献(向上滑动查看) [1]Bennett R, Anderson MA, Seymour JF. Unresolved questions in selection of therapies for treatment-naïve chronic lymphocytic leukemia.J Hematol Oncol. 2023 Jul 8;16(1):72. doi: 10.1186/s13045-023-01469-7