E–F The protein level of eEF2K in mouse heart was detected through western blot analysis, with DOX intervention as before (n = 4). G The expression and distribution of eEF2K in cell DIC models were shown by immunofluorescence. Green signal was used to represent eEF2K, cTnT ...
"Enterprise Architecture is not about building IT models. It’s about solving general management problems." Zachman expressed these sentiments on multiple occasions despite the fact that at least 20 enterprise architecture frameworks exist that attempt to address the above. ...
Experimental Models: Organisms/Strains eEF2K-KO mice [10, 15] N/A eEF2K floxed mice This paper N/A C57BL/6 wild-type mice ENVIGO RMS (ISRAEL) N/A eIF2α-KI Jackson Laboratory Stock number: 017601 Software and Algorithms Graphpad Graphpad http://www.graphpad.com IBM SPSS statistics 21 ...
Close Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily. Email address Sign up I agree my information will be processed in accordance with the Nature and Springer Nature Limited Privacy Policy....
Such inhibitors can be tested in vitro as described herein, and then in vivo using immune-competent mouse models of TNBC6,48,49 and human TNBC-derived xenografts. Importantly, eEf2k null mice are viable and phenotypically normal50, suggesting eEF2K is an ideal target for therapy as its ...
Tumor growth and radioresistance were also evaluated using xenograft models created in nude mice. Results eEF2K expression was higher in ESCC tissues compared with matched non-tumor tissues ( P < 0.05). Proliferation was increased in eEF2K overexpressing cells compared with controls ( P < 0.05),...
It is worth noting that PPI networks generated by different tools (e.g., STRING, IntAct, and BioGRID) may vary, due to possible factors such as differences in data sources, variations in the definition of protein-protein interactions, distinct algorithms and prediction models, updates and time...
This process utilized DiffDock, a model renowned for its state-of-the-art (SOTA) speed and accuracy in deep-learning models for molecular docking. (2) Molecular generation. In this phase, we employed the LiGAN model, which is a pocket-based molecular generation model, to generate candidate ...
The intestinal microbiota in colorectal cancer. Cancer Cell, 2018, 33: 954-964. 【3】 Murphy EF, Cotter PD, Healy S, Marques TM, O'Sullivan O, Fouhy F, et al. Composition and energy harvesting capacity of the gut microbio...
结果 共有354篇英文文献纳入分析,载文量最大的期刊是Cancer Science;日本的发文量及研究成果高影响力在国际上十分突出,其国内的大阪市立大学发文量在所有机构中排名第一;日本作者Yashiro的发文量及共被引频次均居于首位,处于胃硬癌领域核心。该领域研...