Gene ID: 1910 种属 Homo sapiens DNA序列编号: NM_000115.5 DNA描述 Homo sapiens endothelin receptor type B (EDNRB), transcript variant 1, mRNA DNA大小: 4274 bp DNA编码区: atgcagccgcctccaagtctgtgcggacgcgccctggttgcgctggttcttgcctgcggc ctgtcgcggatctggggagaggagagaggcttcccgcctgacagggccactccgcttttg...
27.Van de Putte T, Maruhashi M, Francis A, Nelles L, Kondoh H, Huylebroeck D, Higashi Y. Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome.Am...
The results showed that mouse EDNRB gene was mapped to chromosome 14, which encoded a protein consisting of 442 amino acids with a molecular weight 49430Da. 300bp around transcriptional start site might be promoter regions, which included a CpG island with a length of 1473bp. The promoter ...
Methods EDNRB gene-specific primers were designed and amplified by PCR. The eukaryotic expression vector pCI2-EDNRB was constructed and transfected into MCF-7 cells. The mRNA and protein expression of EDNRB were detected by RT-PCR and Western blot, respectively. MTT assay The proliferation ability...
Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Three transcript variants encoding two different isoforms have been found for this gene. While both isoforms bind ET1, they exhibit different responses upon binding, suggesting that they may be functionally dis...
基因简称(symbol) EDNRB [HGNC] [GeneCards] [NCBI] 基因种类(locus group) protein-coding gene 同源简称(alias symbol) ETB 基因家族代码(gene_family_id) 225 [HGNC] [GenScript] omim代码 131244 entrez码 1910 [Vega] ensembl基因码 ENSG00000136160 [Ensembl] 基因家族(gene family) Endothelin...
目的先天性巨结肠症（Ｈｉｒｓｃｈｓｐｒｕｎｇ’Ｓｄｉｓｅａｓｅ，ＨＤ）是后肠神经元发育不良性疾病，其主要病理特征为从结肠的某一部位（极少数从回肠或空肠）起到直肠末端肠壁内，肌间神经丛（Ａｕｃｒｂａｃｈ丛）和粘膜下神经丛（Ｍｅｉｓｓｎｃｒ丛）内神经节细胞完全缺如。神经节细胞缺如原因尚不清楚。近年来...
Keywords:silver-blackfox;EDNRBgene;tissueexpression * C0rr o gauthor,E-mail:yansq@jlu.edu.CH 银黑狐(silver—blackfox)属哺乳纲食肉目犬科 动物,是赤狐(Vulpesvulpes,redfox)在野生条件 下的毛色突变种,按其基因型不同可分为标准银黑 狐(standardblackfox)和阿拉斯加银黑狐(Alaska black fox) 2 个种 ...
(胃肠外科) 指导教师:**斌教授 答辩日期: 2012-5-23 AdissertationsubmittedtoHuazhongUniversityof ScienceandTechnologyfortheDegreeof DoctorofMedicine StudyofEDNEBgene’ssilencinginducedbymethylated oligonucleotidesinHirschsprung’sdisease’spathogenesis D.Candidate:ZhangWanli Major:Surgery(GastrointestinalSurgery) ...
提供的EDNRB人源重组蛋白(Q02)产品为带有GST标签的人源CDC2L2部分序列重组蛋白,其对应的GeneID号为1910。 产品描述 与其它公司提供的重组蛋白不同,该EDNRB人源重组蛋白(Q02)产品为采用CFS的无细胞麦胚蛋白合成系统表达出来的重组蛋白,可表达出对细胞有毒性、易被蛋白酶降解的蛋白;并获得具有良好的可溶性,并有翻译...