Our understanding of the cellular and molecular mechanisms underlying the adult neural stem cell state remains fragmentary. To provide new models on this issue, we searched for stem cells in the adult brain of the zebrafish. Using BrdU tracing and immunodetection of cell-type-specific markers, we...
Endothelin-1/Edn1 蛋白是一种内皮源性血管收缩肽,在血管调节中发挥着至关重要的作用。作为 G 蛋白偶联受体 EDNRA 和 EDNRB 的可能配体,它在肾小球系膜细胞中启动涉及 PTK2B、BCAR1、BCAR3 以及 GTPases RAP1 和 RHOA 的信号级联,有助于调节血管张力。Endothelin-1/Edn1 Protein, Rat (His-KSI) 是重组的...
Associations of EDNRA and EDN1 polymorphisms with carotid intima media thickness through interactions with gender, regular exercise, and obesity in subjects in Taiwan: Taichung Community Health Study (TCHS). Biomedicine (Taipei) 2015; 5: 8.T.-C. Li, C.-I. Li, L.-N. Liao et al., "...
The results showed that: 1) chicken (c-) EDN1, EDN2, and EDN3 cDNAs were predicted to encode bioactive EDN peptides of 21 amino acids, which show remarkable degree of amino acid sequence identities (91-95%) to their respective mammalian orthologs; 2) chicken (c-) EDNRA expressed in ...