Collaborations that acquire large datasets, such as the GEMRIC consortium, can help translate ECT's clinical efficacy into a better understanding of its mechanisms of action.Belge, Jean-BaptisteRadboud University Medical Centrevan Eijndhoven, Philip...
The mechanism of action of ECT in PD is incompletely understood but seems to involve increased responsiveness to dopamine receptors (92). Pineal melatonin ... Sandyk,Reuven - 《International Journal of Neuroscience》 被引量: 15发表: 1990年 Site and mechanism of the colokinetic action of the gh...
But two decades later, ECT was recalled to treat pharmacotherapy-resistant cases. Avid searches to optimize seizure induction and treatment courses, to reduce risks and fears, to broaden the indications for its use, and to understand its mechanism of action followed. Unlike other medical treatments,...
Many studies indicate a good ECT effectiveness, but, despite its decades-long use, the exact mechanism of action still remains unclear (Bolwig 2011; Farzan et al. 2014; Has- kett 2014; Nie et al. 2022). Side effects can derive both directly from the electri- cal activity induced by...
Electroconvulsive therapy (ECT) is a powerful antidepressive treatment, but its mechanism of action remains poorly understood. To clarify the influence of ECT on corticospinal tract excitability we tested the motor threshold, the motor evoked potential (MEP) input/output curve, and the intracortical ...
One aspect of the controversy is the inconclusive science around the mechanism(s) of ECT, although new findings are emerging (Mulders et al.,Citation2020), and the extent of adverse effects on cognition, especially memory and the discrepancy between objective measures and subjective reports of mem...
Electroconvulsive therapy (ECT) is a highly effective neuromodulatory intervention for treatment-resistant major depressive disorder (MDD). Presently, however, understanding of its neurophysiological effects remains incomplete. In the present study, we u
Anticonvulsant and antidepressant properties of ECT: A proposed mechanism of action Biol Psychiatry, 18 (1983), pp. 1301-1309 View in ScopusGoogle Scholar Sackeim et al., 1986a H Sackeim, P Decina, M Kanzler, B Kerr, S Malitz The efficacy of titrated, low dosage ECT: Effects of electro...
Mechanism of Action the exact MOA by which ECT effects a therapeutic response is unknown Parts of CNS Affected by ECT hormonesneuropeptides neurotrophic facts nearly EVERY neurotransmitter: serotonin, norepinephrine, dopamine Side Effects/Risks of ECT MOST COMMON: TEMPORARY MEMORY LOSS AND CONFUSION-morta...
Cell Proliferation Assays:Cell-based assays are one of the key tools to measure mechanism of action responses to certain stimuli such as growth factors, cytokines and other media components. The flow cytometer can measure proliferation by labeling resting cells with a cell membrane fluorescent dye, ...