Gene ID: 1893 种属 Homo sapiens DNA序列编号: NM_004425.4 DNA描述 Homo sapiens extracellular matrix protein 1 (ECM1), transcript variant 1, mRNA DNA大小: 2046 bp DNA编码区: atggggaccacagccagagcagccttggtcttgacctatttggctgttgcttctgctgcc tctgagggaggcttcacggctacaggacagaggcagctgaggccagagcactttcaagaa...
提供的ECM1人源重组蛋白(P01)产品为带有GST标签的人源ECM1全长序列重组蛋白,其对应的GeneID号为1893。 产品描述 与其它公司提供的重组蛋白不同,该ECM1人源全长重组蛋白(P01)产品为采用CFS的无细胞麦胚蛋白合成系统表达出来的重组蛋白,可表达出对细胞有毒性、易被蛋白酶降解的蛋白;并获得具有良好的可溶性,并有翻...
ECM1 genelipoid proteinosismutationBackground Lipoid proteinosis (LP), also known as Urbach–Wiethe disease, is a rare autosomal recessive disorder characterized by a hoarse voice, warty skin infiltration and scarring. Mutations within the extracellular matrix protein 1 (ECM1) gene cause LP. ...
参考文献[1]ChanI,LiuL,HamadaT,eta1.Themolecularbasisoflipoidpro-teinosis:mutationsinextracellularmatrixprotein1.ExpDermatol,2007,16(11):881-890.[2]HamadaT,McLeanWH,RamsayM,eta1.Lipoidproteinosismapstolq21andiscausedbymutationsintheextracellularmatrixPtein1gene(ECM1).HumMolC,enet,2002,1l(7):833...
ToinvestigatetheexpressionandsignificanceoftheECM1geneincolorectalcancertissue.METHODS:BasedonTaqMan-MGBmethodol-ogy,realtimequantitativepolymerasechainre-action(RQ-PCR)wasusedtodetectthemRNAlevelsofECM1intissuefromnormalcontrols(n=46),colorectaladenoma(n=18),colorectalcancerwithoutlymphaticmetastasis(n=25)and...
在本发明中,术语“ecm1基因”、“ecm1多核苷酸”或“细胞外基质蛋白基因ecm1”可互换使用,都指具有小鼠ecm1核苷酸序列(geneid:13601)的核酸序列。需理解的是,当编码相同的氨基酸时,密码子中核苷酸的取代是可接受的。另外需理解的是,由核苷酸取代而产生保守的氨基酸取代时,核苷酸的变换也是可被接受的。
This resulted in a frame shift from codon 169 and appearance of a premature stop codon at 177, causing formation of a mutated protein (176 amino acids) instead of normal ECM1 protein (540 amino acids).Conclusion: A case of homozygous 62-bp insertion in ECM1 gene causing lipoid proteinosis...
工作原理人细胞外基质蛋白1(ECM1)elisa试剂盒 目的探讨HIST1H1E基因突变致Rahman综合征的临床及遗传学特点.方法回顾性分析2018年6月收治的1例Rahman综合征患儿的临床资料.以Rahman综合征,HIST1H1E基因,组蛋白H1,突变,Rahman syndrome,HIST1H1E gene,Histone H1为检索词,检索建库至2019年12月中国知网,万方数据库,...
Homozygous missense mutation in the ECM1 gene in Chinese siblings with lipoid proteinosis[J]. Acta Derm Venereol,2007,87(5):387-389. [4] Sercu S, Zhang L, Merreqaert J. The extracellular matrix protein1:its molecular interaction and implication in tumor progression[J].Cancer Invest,2008,26...
Splice variants: Alternative splicing may create different sized proteins from the same gene.2. Relative charge: The composition of amino acids may affects the charge of the protein.3. Post-translational modification: Phosphorylation, glycosylation, methylation etc.4. Post-translation cleavage: Many ...