Histologically, ECL cell hyperplasia were shown in all patients. However, no relationship was found between serum gastrin levels and the number of CgA positive ECL cells. There was also no relationship between serum gastrin levels and the proportion of Ki67 positive cells or the density of CCKBR ...
usually secondary to adrenal neoplasia (in dogs) or neoplasia or hyperplasia (cats) (Kooistra 2020). Cats are usually middle aged or older and are presented with clinical signs related to muscular weakness (such as ventroflexion, from hypokalemia) and hypertension (from sodium and water retention...
ECL cell activity is strongly stimulated by gastrin, which, once applied as a long-standing stimulus, also exerts a potent proliferating effect. Long-lasting hypergastrinaemia has been demonstrated to elicit ECL cell proliferation in laboratory animals, inducing ECL cell hyperplasia, dysplasia and ECL...
Carcinoid (ECL cell) tumor of the oxyntic mucosa of the stomach: A hormone-dependent neoplasm? In: Fenoglio-Preiser C, Wolff M, Rilke F, eds. Progress in Surgical Pathology. Philadelphia: Field & Wood, 1988; 8:177-195.Bordi C, D'Adda T, Pilato FP, Ferrari C. Carcinoid (ECL cell)...
At similar gastrin levels, ECL-cell hyperplasia of the same magnitude developed during both ranitidine and omeprazole treatment. Antrectomy prevented the development of ECL-cell hyperplasia during omeprazole treatment, indicating that the hyperplasia was not due to the drug treatment per se, but ...