Several protease inhibitors were found in the seeds of a Cucurbitacea, Ecballium elaterium, and were separated from one another by affinity and molecular sieve chromatography. Three main trypsin isoinhibitors were purified by ion-exchange chromatography and the sequence of the major one, EETI II, ...
Ecballium elaterium - Mediterranean vine having oblong fruit that when ripe expels its seeds and juice violently when touched exploding cucumber, squirting cucumber, touch-me-not gourd vine, gourd - any vine of the family Cucurbitaceae that bears fruits with hard rinds Ecballium, genus Ecballium -...
seeds (Pathan et al., 2011) as well as anti-inflammatory and analgesic properties of Commiphora myrrha (Su et al., 2011). The anti-inflammatory effect of Ecballium elaterium Fruit Juice is also has been reported (Yesilada et al., 1988). Mentha pulegium L. exhibits antioxidant and MAO-A ...
Protease inhibitors from Ecballium elaterium seeds.Upper Airway Edema Resulting From Use of Ecballium elateriumStructure of Ecballium elaterium trypsin inhibitor II (EETI-II): a rigid molecular scaffold.Isolation of an Anti-inflammatory Principle from the Fruit Juice of Ecballium elateriumImpacts of floral...
From ethnobotanical and scientific records, adverse effects and reactions have been mostly related to medicinal sources within the plant other than the seeds. These toxic effects are primarily caused by the juice surrounding the seeds.doi:10.1016/B978-0-12-375688-6.10128-8Everaldo Attard...
Use of Extracts from Squirting Cucumber ( Ecballium elaterium ) Seeds in Healthdoi:10.1016/b978-0-12-375688-6.10128-8Everaldo AttardAcademic Press
(2008) Antitrypsin activity of extracts from Ecballium elaterium seeds. Fitoterapia, Vol. 79, No. 3, pp. 226-228, ISSN 0367-326XAttard E, Attard H. Antitrypsin activity of extract from Ecballium elaterium seeds. Fitoterapia. 2008. 79(3): 226-228....
Fruit glaucous-green, oblong, or oblong-ovoid, bristly, obtuse at both ends, (3)4–6cm long, 1.5–2.5(3) cm wide, when ripe detaching from pedicel and violently ejecting seeds and mucus via aperture thus formed; seeds small, elongate, flattened, smooth, narrowly bordered, ca. 4mm long...
Methods: The air-dried and powdered fruits, seeds, and roots of E. elaterium were extracted using three solvents with different polarities, n-Hexane (n-Hex), dichloromethane (DCM), and methanol (MeOH). The MeOH extract of roots was subjected to fractionalizing by a C18 Sep-Pak cartridge...
Microproteins with proteinase inhibitory activity, 28 to 30 amino acids long, with 3 disulfide bridges have been isolated from Ecballium elaterium seeds. A peptide (EETI II) was isolated and behaved as a powerful trypsin inhibitor (Kd = 10(-11) to 10(-12) M). It was sequenced, chemically...