OBJECTIVE: To determine whether clinical presentation or early CT findings of patients enrolled in the first European Cooperative Acute Stroke Study (ECASS I) trial would identify lacunar infarcts before treatment. METHODS: Predictive values, sensitivity, specificity, and accuracy of clinical presentation ...
but the results of each trial did not support its use beyond 3 hours.都是证明阿替普酶静脉溶栓...
溶 疗实践习惯改变极慢,对溶栓仍持怀疑的态 栓的影像评估试验 EchoplanarImaging Evaluation 度,加之溶栓时间窗的限制,导致实际溶栓率 ThrombolyticTrial,EPITHET B31 很低。在欧美,非专业中心医院的溶栓治疗率 是2008年发表的澳大利亚的研究,依据MRI 万方数据 JStroke,Jan2009,Vol4,No.I ⅢChin 所见不匹配而扩大...
Results of the thrombolysis in myocardial infarction (TIMI) phase II trial. N Engl J Med 320:618–627 Article Google Scholar van Swieten JC, Koudstaal PJ, Visser MC, Schouten HJA, van Gijn J (1988) Interobserver agreement for the assessment of handicap in stroke patients. Stroke 19:604...
European Cooperative Acute Stroke Study: Trial Protocol The European Cooperative Acute Stroke Study (ECASS) is a double-blind, randomized placebo controlled trial of rt-PA (alteplase) in acute ischemic hemispheric stroke in which thrombolysis is initiated 1鈥 6 h following the onset of symptom......
ECASS I,5 a European multicentre trial, used a maximum interval from onset to treatment of 6 h and a higher dose of alteplase (1·1 mg/kg). No significant differences between alteplase and placebo were seen in the median scores of the primary outcome measures, probably because a significant...
but the results of each trial did not support its use beyond 3 hours.都是证明阿替普酶静脉溶栓...
The European Cooperative Acute Stroke Study (ECASS) is a double-blind, randomized placebo controlled trial of rt-PA (alteplase) in acute ischemic hemispheric stroke in which thrombolysis is initiated 1鈥 6 h following the onset of symptom... C Argentino,W Hacke,M Kaste,... - Springer Japan...
ECASS II =-=[3]-=-, a multicentred European trial of 800 patients, using Alteplase (0.9 mg/kg) intravenously (IV), combined with strict CT and blood pressure inclusion criteria, supported the use of Alteplase within 3 ...Ford G,Freemantle N.ECASS-II: intravenous alteplase in acute ...
In the USA, recombinant tissue plasminogen activator (rt-PA) has been approved for therapy of acute ischemic stroke (AIS) within a 3 hour time window based on the results of the NINDS [1] trial. Only few patients with AIS are referred to a hospital within three hours after onset of ...