Pathways significantly enriched by nonsilent mutations of each LCL were totally different among all LCLs. In conclusion, high-passage LCLs may not be suitable to serve as APCs due to random nonsilent mutations, particularly for presentation of neoantigens of low immunogenicity, although further ...
人类外周血B 淋巴细胞可以被EB 病毒（Epstin-Barr V irus,EBV ）在适当的体外环境中转化成具有永生化特征的人类淋巴母细胞系（lymphoblastoid cell lines,LCL ）。该细胞株保存了各人的完整基因组，且其生化和分子生物学特征不发生变化]2,1[。因此，利用EBV 建立具有人类全基因组的永生化细胞株，成为保全全世界各...
Epstein–Barr virus nuclear antigen 3C (EBNA-3C) is a small subset of latent antigens critical for the transformation of human primary B lymphocytes into continuously proliferating lymphoblastoid cell lines (LCLs)in vitrothrough manipulation of a number of major cellular pathways. Moreover, EBNA-3C ...
人类成淋巴细胞系 GM24385 (LCL from B-Lymphocyte) 小鼠骨髓瘤淋巴母细胞 /杂交瘤B淋巴细胞 IVA12 小鼠骨髓淋巴母细胞 32D clone3 人类成淋巴细胞 GM12891 (LCL from B-Lymphocyte) 人类成淋巴细胞 GM12892 (LCL from B-Lymphocyte) 小鼠T淋巴瘤细胞 E.G7-0VA 小鼠淋巴瘤细胞 Nb2-11 Cell Line from ra...
A Nanoparticles tracking analysis and representative plots showing size distributions and concentrations of EV produced by 20.106 LCL (i.e. J1209) and 30.106 DLBCL (i.e. SUDHL6) cell lines after 72 h of culture. Plots represent the mean value (black line) with SD (red shaded area) from ...
(HLCL 21B8细胞系)人类淋巴母细胞瘤细胞HLCL 21B8细胞、(HLCL 14C1细胞系)人类淋巴母细胞瘤细胞HLCL 14C1细胞 (Human Cell line 1D3细胞系)人类粒细胞系Human Cell line 1D3细胞、(L/1C2细胞系)小鼠杂交瘤细胞L/1C2细胞 (CHO 1beta9,12.5 Clone 36细胞系)中国仓鼠卵巢细胞(亚系克隆)CHO 1beta9,12...
HLCL 7D7人类淋巴母细胞瘤细胞 HLCL 9B10人类淋巴母细胞瘤细胞 HLCL 9C3 人类淋巴母细胞瘤细胞 HMy2.CIR人B淋巴母细胞 WIL2-S [WIL2S]人B淋巴细胞 A3人T淋巴细胞白血病细胞 H9人T淋巴瘤细胞 HYL EB病毒转化的人B淋巴细胞(彝族) I 2.1 人急性T淋巴细胞性白血病细胞 ...
(29–31). These molecules are transiently induced at high levels when these cells are transformed into LCLs and the majority of them play a role in LCL proliferation. Both CD80 and CD86 are members of the immunoglobulin (Ig) super-gene family and are expressed on many cell types, including...
Akata cell line is of Burkitt׳s lymphoma origin and is latently infected with EBV (Takada et al., 1991). Human Embryonic Kidney HEK293, 293T and HeLa are EBV negative cell lines. B95-8 cells, LCL2 and Akata cells were maintained in RPMI-1640 (Lonza, Basel, Switzerland, Cat no. ...
The decrease of TRAF2 RNA was confirmed in the lymphoma cell line BCKN-1 after knockdown of LMP2A. To evaluate the mechanism by which LMP2A regulates TRAF2 expression, we transfected one LCL and one lymphoma cell line (LCL9001 and BCKN-1, respectively) with siRNA to LMP2A, extracted ...