The diagnostic algorithm proposed by the Belgian Superior Health Council is merely directive and each individual lab remains responsible for the interpretation and implementation of test combinations for the detection of EBV infections. Our study shows the limited added value of testing for EA IgG and...
Test results most likely indicate the following: VCA-IgM VCA-IgG EA-D, IgG EBNA, IgG Possible Interpretation Negative Negative Negative Negative No infection, symptoms due to another cause, susceptible to EBV infection Positive Positive Negative Negative Early, primary infection Negative or positive Po...
Latent membrane protein 1 (LMP1) is a major Epstein–Barr virus (EBV)-encoded oncoprotein involved in latency infection that regulates mitochondrial functions to facilitate cell survival. Recently, mitochondrial fission has been demonstrated as a crucial
The scope of immune monitoring is to define the existence, magnitude, and quality of immune mechanisms operational in a host. In clinical trials and praxis, the assessment of humoral immunity is commonly confined to measurements of serum antibody reactiv
cancers Article EBV Positive Diffuse Large B Cell Lymphoma and Chronic Lymphocytic Leukemia Patients Exhibit Increased Anti-dUTPase Antibodies Marshall Williams 1,2 and Maria Eugenia Ariza 1,2,* 1 Department of Cancer Biology and Genetics, The Ohio State University College of Medicine, Columbus, OH ...
Background: Epstein–Barr virus (EBV) is often kept silent and asymptomatic; however, its reactivation induces a chronic and/or recurrent infection that is associated with numerous diseases, including cancer and inflammation-related disorders. As no spec
cancers Article The EBV-Encoded Oncoprotein, LMP1, Induces an Epithelial-to-Mesenchymal Transition (EMT) via Its CTAR1 Domain through Integrin-Mediated ERK-MAPK Signalling Mhairi A. Morris 1,† ID , Louise Laverick 2,†, Wenbin Wei 3,4 ID , Alexandra M. Davis 5, Samantha O'Neill 5, ...