[2]Pant S,et al.Lymph-node-targeted, mKRAS-specific amphiphile vaccine in pancreatic and colorectal cancer: the phase 1 AMPLIFY-201 trial[J].Nature medicine,2024:1-12. https://www.nature.com/articles/s41591-023-02760-...
徐瑞华作为通讯或第一作者在国际顶级期刊jama,nature medicine,nature materials,cancer cell,lancet oncology等发表高水平论文200余篇,入选科睿唯安(clarivate analytics)全球高被引科学家,连续入选中国高被引学者榜单;以第一完成人获国家科技进步二等奖2项,...
2023年3月21日南京大学医学院何素素和李尔广团队在《Nucleic Acids Research》在线发表了题为“LINE-1 repression inEpstein-Barr virus-associated gastric cancer through viral-host genome interaction”的研究论文。该研究发现了EBV相关胃癌(EBVaGC)中LINE-1表达受抑制,尤其是位于内含子区域、进化年龄偏年轻、序列长度...
10月7日，中南大学湘雅医学院附属肿瘤医院罗湘建团队在《Journal of Experimental & Clinical Cancer Research》上发表题为“Anoikis resistance and immune escape mediated by Epstein-Barr virus-encoded latent membrane protein 1-induced stabilization of PGC-1α promotes invasion and metastasis of nasopharyngeal car...
Cancer Center, Houston, TX, USA. His studies showed that EBV-positive DLBCL exhibited rare genetic alterations. However, similar to other EBV-positive LPDs, EBV-positive DLBCL more frequently expressed NF-κB p50, phosphorylated STAT-3 and CD30 compared with EBV-negative DLBCL.11,12,13Here, ...
中国临床肿瘤学会理事长,中国抗癌协会副理事长,中国抗癌协会靶向治疗专委会首届主任委员,中国抗癌协会化疗专委会候任主任委员,中国临床肿瘤学会肠癌专委会主任委员,《Cancer Communications》主编,研究生教材《肿瘤学》主编,本科生教材《临床肿瘤学》主编。徐瑞华作为通讯或第一作者在国际顶级期刊JAMA、Nature Medicine、Natu...
In this cancer model, we identified the major host targets of latent membrane protein 1 which is a driving oncogene encoded by Epstein-Barr virus in latency infection. latent membrane protein 1 activates several oncogenic signaling axes causing multiple malignant phenotypes and therapeutic resistance. ...
In addition, results were published by Old and associates suggesting that EBV might be a factor in the etiology of nasopharyngeal carcinoma (NPC), a high-incidence cancer in Africa and Southeast Asia (Old et ah , 1966). These initial disease associations, established largely from sero...
近日,香港中文大学李嘉诚健康科学研究所的Y.M. Dennis Lo团队在Cancer Cell期刊发表了题目为Fragmentomics profiling and quantification of plasma Epstein-Barr virus DNA enhance prediction of future nasopharyngeal carcinoma的研究论文。 本研究囊括了大约 20,000 名(接受两轮筛查)受试者的前瞻性队列,研究人员发现与...
[8]Henter JI, Horne AC, Arico M, et al.HLH-2004: Diagnostic and therapeuticguidelines for hemophagocytic lymphohistiocytosis[J]. Pediatr BloodCancer,2007,48(2):124-131. [9]Fryer JF,Heath AB,Wilkinson DE,et al.A collaborative study to establish the 1st ...