The virus affiliates with the immune system of the host which aids to determine the dynamics as to how the virus functions and affects the immune system. After sequencing the Ebola virus genome, it has attracted the researchers, especially from Bioinformatics, Genomics, Transcriptomics, Proteomics ...
Genome Biol. 18, 4 (2017). Article PubMed PubMed Central Google Scholar McMullan, L. K. et al. Characterisation of infectious Ebola virus from the ongoing outbreak to guide response activities in the Democratic Republic of the Congo: a phylogenetic and in vitro analysis. Lancet Infect. ...
EBOLA virus diseaseGENETICSThe article discusses research by Pardis Sabeti in the August 2014 issue of "Science" magazine which reports the genome sequencing of Ebola virus samples from the epidemic-hit Sierra Leone, suggesting direct patient-to-patient transmission and discussing the viral lineage....
Genome Biol. 18, 4 (2017). Article PubMed PubMed Central Google Scholar McMullan, L. K. et al. Characterisation of infectious Ebola virus from the ongoing outbreak to guide response activities in the Democratic Republic of the Congo: a phylogenetic and in vitro analysis. Lancet Infect. ...
Each Ebola virus carries a helical single-stranded negative-sense RNA genome of about 19,000 nucleotides. It shows a tubular/cylindrical shape, which contains viral envelope, matrix, and nucleocapsid components. Generally, it is about 920 nm long with a diameter of 80 nm (Klenk and Feldmann, ...
so that the regional level patterns and drivers of the epidemic across its entire duration have remained uncertain. Using 1,610 genome sequences collected throughout the epidemic, representing over 5% of recorded Ebola virus disease (EVD) cases (Extended Data Fig. 1), we reconstruct a detailed ...
nouna severe and often fatal disease in humans and nonhuman primates (monkeys and chimpanzees) caused by the Ebola virus Synonyms Ebola fever Ebola hemorrhagic fever Related Words haemorrhagic fever hemorrhagic fever VHF viral haemorrhagic fever
Then, viral RNA is transcripted into viral proteins and viral genome is replicated followed by encapsidation, assembly and budding of a new virion. EBOV: Ebola virus; ESCRT: Endosomal sorting complexes required for transport; GP: Glycoprotein; TIM-1: T-cell immunoglobulin and mucin domain 1; ...
The 2013–2016 West African epidemic caused by the Ebola virus was of unprecedented magnitude, duration and impact. Here we reconstruct the dispersal, proliferation and decline of Ebola virus throughout the region by analysing 1,610 Ebola virus genomes, which represent over 5% of the known cases...
Banadyga, L., Hoenen, T., Ambroggio, X.et al.Ebola virus VP24 interacts with NP to facilitate nucleocapsid assembly and genome packaging.Sci Rep7, 7698 (2017). https://doi.org/10.1038/s41598-017-08167-8 Download citation Received04 May 2017 ...