Here we show that EB1 formed molecular condensates through liquid鈥搇iquid phase separation (LLPS) to constitute the microtubule plus-end machinery. EB1 LLPS is driven by multivalent interactions among different segments, which are modulated by charged residues in the linker region. Phase-separated...
Here we show that EB1 formed molecular condensates through liquid–liquid phase separation (LLPS) to constitute the microtubule plus-end machinery. EB1 LLPS is driven by multivalent interactions among different segments, which are modulated by charged residues in the linker region. Phase-separated ...
2022年12月19日,无膜细胞器与细胞动力学教育部重点实验室姚雪彪教授和刘行教授联合攻关团队在Nature Cell Biology杂志上在线发表了题为Phase separation of EB1 guides microtubule plus-end dynamics的研究论文,揭示了液液相分离驱动EB1蛋白形成纳米催化器的物理化学机制,解析了从酵母到人进化上保守的EB1相分离的化学...
Phase separation of EB1 guides microtubule plus-end dynamics Article 19 December 2022 Combining optogenetics with sensitive FRET imaging to monitor local microtubule manipulations Article Open access 07 April 2020 Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the mic...
Polypropylene (PP) hollow fiber microfiltration membranes with excellent performance were successfully prepared from the PP-binary diluent system via thermally induced liquid–liquid (L–L) phase separation method. The binary diluent consisted of myristic acid and diphenyl carbonate. The effects of the ...
A novel method through solid phase extraction combined with gradient elution for concentration and separation of 66 (ultra) trace persistent toxic pollutants in Antarctic waters Li,Zhang,Guang-Shui,... - 《Chinese Chemical Letters》 - 2016 - 被引量: 0 收藏 相关文章 碳纳米管/邻苯二甲腈树脂薄膜...
10月21日,细胞应激生物学国家重点实验室、细胞信号网络协同创新中心、厦门大学生命科学学院的周大旺和陈兰芬课题组合作在Cell杂志上发表了题为Glycogen accumulation and phase separation drives liver tumor initiation的研究论文。 在这项工作中,作者通过构建多种小鼠肝癌模型,分析早期阶...
杂志在线发表标题为“ histone h2b.8 compacts flowering plant sperm via chromatin phase separation ”的研究论文,该研究表明组蛋白变体h2b.8在拟南芥中介导精子染色质和核凝结。这项研究揭示了一种通过未表达染色质的全局聚集而形成的核压...
In order to prepare flexible and ion conductive deoxyribonucleic acid (DNA) films without phase separation, DNA was modified with poly(ethylene oxide) (PEO... N Nishimura,S Kokubo,H Ohno - 《Polymers for Advanced Technologies》 被引量: 3发表: 2010年 Expression profiling of M2PK in 19 differe...
A one-dimensional thermal model is developed to evaluate the effect of radiation on the phase change of lithium-fluoride (LiF) in an annular canister under gravitational and microgravitational conditions. Specified heat flux at the outer wall of the canister models focused solar flux; adiabatic and...