The R6/1 mouse model of the disease recapitulates the adult onset of motor symptoms preceded by cognitive and affective deficits. The monoaminergic systems participate in the establishment of motor and cognitive loops and we postulated that their organization and interaction could be precociously ...
Therefore, it is currently unclear which RMTs are the most suitable to detect functional decline symptoms robustly and accurately in patients with early-stage AD. The Remote Assessment of Disease and Relapse - Alzheimer’s Disease (RADAR-AD; https://www.radar-ad.org/) study aimed to evaluate...
Monofocal episode: The episode affects one part of your brain or spinal cord. Multifocal episode: The episode affects many parts of your brain or spinal cord. CIS symptoms are a lot like MS symptoms. The difference is that CIS is only one episode. MS is a chronic condition. Which symptoms...
Therefore, it is currently unclear which RMTs are the most suitable to detect functional decline symptoms robustly and accurately in patients with early-stage AD. The Remote Assessment of Disease and Relapse - Alzheimer’s Disease (RADAR-AD; https://www.radar-ad.org/) study aimed to evaluate...
Accurate diagnosis of Alzheimer’s disease (AD) in its earliest stage can prevent the disease and delay the symptoms. Therefore, more sensitive, non-invasive, and simple screening tools are required for the early diagnosis and monitoring of AD. Here, we design a self-assembled nanoparticle-mediat...
Monofocal episode: The episode affects one part of your brain or spinal cord. Multifocal episode: The episode affects many parts of your brain or spinal cord. CIS symptoms are a lot like MS symptoms. The difference is that CIS is only one episode. MS is a chronic condition. Which symptoms...
Ischemic stroke (IS), a devastating cerebrovascular accident, presents with high mortality and morbidity. Following IS onset, a cascade of pathological changes, including excitotoxicity, inflammatory damage, and blood-brain barrier disruption, significan
In addition, symptoms do not always present concurrently. This diversity of symptomatic expression adds to the difficulty in initial diagnosis. Armed with the recently refined criteria for diagnosis, specialists, such as rheumatologists, primary care physicians, ophthalmologists, and dentists, who would ...
Get information about the various symptoms you may see during your first month of pregnancy—such as spotting, mood swings, and fatigue—and why you experience them.
Lifetime exposure to traffic-related air pollution and symptoms of depression and anxiety at age 12 years. Environ Res. 2019;173:199–206. Article CAS PubMed PubMed Central Google Scholar St-Cyr S, McGowan PO. Adaptation or pathology? The role of prenatal stressor type and intensity in ...