Recognition of Zika virus (ZIKV) sexual transmission (ST) among humans challenges our understanding of the maintenance of mosquito-borne viruses in nature. Here we dissected the relative contributions of the components of male reproductive system (MRS) d
Twenty-seven immunocompromised patients with active herpes zoster were included. Clinical data, cerebrospinal fluid (CSF) analysis, and treatment outcomes were analyzed. RESULTS. The mean age was 45 years, with a predominance of males (60%). Most patients had HIV (16) with a mean CD4 count ...
In the late-onset group, 1 had trisomy 21, 1 had partial trisomy 22, 1 had Klinefelter syndrome, and 8 had CNVs, of which 1 case had a microdeletion [seq [hg19]del (17) (p11.2)] suggesting Smith–Magenis syndrome, which may lead to severe neurological symptoms. Prognostic outcomes ...
Early-life trauma (ELT) is a risk factor for binge eating and obesity later in life, yet the neural circuits that underlie this association have not been addressed. Here, we show in mice that downregulation of the leptin receptor (Lepr) in the lateral hypothalamus (LH) and its effect on ...
It's caused by viruses invading the brain, such as herpes and enteroviruses. Mosquitoes and ticks can also transmit viruses which can cause encephalitis. Symptoms develop quickly, over days to weeks. Most people with infectious encephalitis start with symptoms such as headache and fever. These can...
These findings suggest new strategies to remediate the effect of childhood trauma before the onset of clinical symptoms, such as anti-inflammatory interventions and potentiation of adaptive immunity. Similar strategies might be used to ameliorate the unfavorable treatment response described in psychiatric ...
. This increase is due to modifications of diagnostic criteria, wider access to diagnosis, and a genuine increase due to a combination of genetic and environmental components4,5. In spite of the incidence of autism, there is yet no FDA or EMA approved drug agent to treat its core symptoms....
(ROC) curve were employed to examine the discrimination between the two types of diseases based on neuropsychiatric symptoms and laboratory results. Compared to patients with neurological autoimmune diseases, patients with CNS virus infections had a higher incidence of abnormal behavior (p= 0.026) and...
and these levels were further increased in the severe cases. Patients with severe COVID-19 and vancomycin-resistant enterococci (VRE) bacteremia had elevated calprotectin levels, but their C-reactive protein and procalcitonin levels were not increased. Fungal superinfections and herpes simplex virus re...
The rubella virus (RV) was the first virus shown to be teratogenic in humans. The wealth of data on the clinical symptoms associated with congenital rubella syndrome is in stark contrast to an incomplete understanding of the forces leading to the teratog