doi:10.1523/ENEURO.0108-24.2024Sutter, KatrinOostwoud Wijdenes, Leonievan Beers, Robert J.Claassen, Jurgen A. H. R.Kessels, Roy P. C.Medendorp, W. PietereNeuro
Two experiments examined whether impairments in recognition memory in early stage Alzheimer's disease (AD) were due to deficits in encoding contextual information. Normal elderly (NE) and patients diagnosed with mild stage AD learned one of two tasks. In Experiment 1 correct recognition memory requir...
Alzheimer's disease affects the parts of the brain that control thought, memory and language, the result of progressive and irreversible loss of synapses and neural circuitry. As the disease progresses, symptoms can increase from mild memory loss to losing the ability to communicate and respond to...
Cognitive training and cognitive rehabilitation for people with early-stage Alzheimer's disease: A review Memory difficulties are a defining feature of Alzheimer's disease (AD), with significant implications for people with AD and family members. Interventions aimed at helping with memory difficulties,...
Alzheimer's take place among proteins up to 20 years earlier. A two-tier method developed at Ruhr-Universität Bochum (RUB) can detect the disease at a much earlier stage. The researchers from Bochum have published their report inAlzheimer's and Dementia: Diagnosis, Assessment and Disease ...
(2006). Detecting early-stage Alzheimer's disease in MCI and PreMCI: The value of informants. In M. Jucker, K. Beyreuther, C. Haass, & Y. Christen (Eds.). Alzheimer: 100 Years and Beyond, Research and Perspectives in Alzheimer's Disease (pp. 392-397). Heidelberg, Berlin: Springer...
Modeling brain‐predicted age from functional connectivity in early‐stage and preclinical Alzheimer disease The "brain‐predicted age" approach summarizes complex age relationships with neuroimaging features by quantifying apparent brain age compared to normative trajectories. Advanced brain‐predicted age has...
Touchon, J
Blood acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activities have been studied as markers for Alzheimer’s disease (AD), but their usefulness as a disease marker is controversial. To determine cholinesterase (ChE) activity during AD progression and whether ChE changes associate to...
The disrupted metabolism of sugar, fat and calcium is part of the process that causes the death of neurons in Alzheimer's disease. Researchers from Karolinska Institutet in Sweden have now shown, for the first time, how important parts of the nerve cell