Objective of the study: To evaluate the value of serum creatine phosphokinase-brain specific (CK-BB) and urinary lactate/creatinine (L/C) ratio as early indicators of brain damage in fullterm newborns with hypoxic ischemic encephalopathy (HIE). Patients and methods: A case-control...
The predictive value of specific clinical signs at age 3–5 hours for an abnormal 6-hour aEEG. The specific clinical signs we analyzed were those used as entry criteria in the cooling trials with abnormal aEEG as an additional criterion [15–17]. These clinical signs included decreased...
Geneticists have found signs of at least three waves of migration over the following millennia. There is no evidence that domestic dogs accompanied them.“We don’t know if dogs were part of the first waves of immigration to the Americas” says Luc Janssens of Ghent University in Belgium. “...
Seizures are more common in the neonatal period than in any other time of life, most of them occurring in the first week of life. Neonatal seizures frequently present just with subtle signs, or are entirely nonconvulsive, with no clinical manifestation and may be only detectable by electroencep...
In shock states, blood flow to the brain and heart is maintained owing to the redistribution of blood away from peripheral organs, enhances bacterial transloca- tion, and leads to multiple organ dysfunction [20]. Thus, in neonatal EOS with clinical suspicion of shock, signs of shock must be...
In a new study published in Nature Communications, researchers observed 65 newborn babies who had received a standard heel-prick blood test to look for signs of potential infection. When a baby's blood test result suggested they may have an infection, which required further antibiotic treatment,...
Luise A. Cullen-McEwen2, Russell D. Brown3, Rod J. Snow4, David W. Walker1, Michelle M. Kett3 and Hayley Dickinson1 Background: Acute kidney injury affects ~70% of asphyxi- ated newborns, and increases their risk of developing chronic kidney disease later in ...
(newborn–4 years)2,13,16,27–32,36,40,41,51 Fabry-related signs and symptoms Earliest report of symptom Storage of globotriaosylceramide found in organs on biopsy Prenatal Corneal whorls/verticillata Prenatal/ newborn Gastrointestinal problems, including nausea, vomiting, diarrhea, constipation, ...
avoid a series of serious complications caused by excessive fluctuation of blood sugar, promote the stability of vital signs of newborns, reduce the hospitalization rate of newborns, improve the success rate of breastfeeding, reduce uterine contraction/wound pain, and reduce the incidence of postpartu...
(Fig.4e). We also observed signs of altered nicotinamide adenine dinucleotide (NAD) metabolism in SURF1 DNs, as shown by low amount of NAD and NADP (Fig.4e) and low expression of enzymes involved in NAD and NADP metabolism (NAMPT, GPD1, G6PD1) (Fig.4c, d, Supplementary Data5). ...