Parkinson’s is caused by the loss of brain cells responsible for making a chemical messenger called dopamine. The lack of dopamine signaling is ultimately what gives rise to most symptoms of Parkinson’s disease.Motor symptomsParkinson’s disease is characterized by changes in movement. The ...
Read the full-text online article and more details about "Symptoms Usually Mild in Early Parkinson's" by Dr. Paul Donohue - St Louis Post-Dispatch (MO), July 1, 1996By Dr. Paul Donohue
The following points should be borne in mind regarding Parkinson’s disease symptoms: Although most people will have a number of signs, a person does not need to exhibitallof the symptoms to be diagnosed with Parkinson’s disease. Parkinson’s is usually unilateral (1 side) at the early stag...
doi:10.1007/s10048-025-00810-1Early-onset Parkinson’s diseaseGBA1Gaucher diseaseParkinson’s diseaseWhole exome sequencingParkinson's disease (PD) is a multifaceted neurodegenerative disorder with both non-motor and motor symptoms. Variants in the glucosylceramidase beta 1 (GBA1) gene are the str...
Psychiatric complaints are common in Parkinson's disease (PD), and have a significant influence in disease outcome and quality of life. Little attention has been paid to psychiatric symptoms at early stage disease. We aimed to screen a population of early stage PD patients for psychiatric symptoms...
Prasinezumab, a monoclonal antibody that binds aggregated α-synuclein, is being investigated as a potential disease-modifying therapy in early-stage Parkinson’s disease. Although in the PASADENA phase 2 study, the primary endpoint (Movement Disorder So
While movement problems are the main symptom of Parkinson's disease, a new study shows that even early in the course of disease people frequently experience many non-motor symptoms such as drooling, anxiety and constipation. The study is published in the
Prasinezumab, a monoclonal antibody that binds aggregated α-synuclein, is being investigated as a potential disease-modifying therapy in early-stage Parkinson’s disease. Although in the PASADENA phase 2 study, the primary endpoint (Movement Disorder So
This cohort study of women in the Nurses’ Health Study II assesses the association of obesity and weight gain since early adulthood with early-onset
Joanne P. RobinsonSchool of NursingRutgers UniversityCamdenNew JerseyChristine W. BradwaySchool of NursingUniversity of PennsylvaniaPhiladelphiaPennsylvaniaLisette Bunting‐PerrySchool of NursingUniversity of DelawareNewarkDelawareHelene MoriartyM. Louise Fitzpatrick College of NursingVillanova UniversityVillanova...