It generates a diagnosis of common mental disorders, according to the Tenth Revision of the International Classification of Diseases of the World Health Organization diagnostic criteria (ICD-10). Level of loneliness was assessed by the validated Chinese version of the 6-item De Jong Gierverg’s ...
The participant must have been assigned an ICD-10 diagnosis of Alzheimer’s disease (AD), vascular dementia, or mixed AD and vascular dementia. AD accounts for 62% of dementia diagnoses, and vascular dementia for 17%, with mixed AD and vascular dementia accounting for a further 10% [2]....
Plasma metabolites of aromatic amino acids associate with clinical severity and gut microbiota of Parkinson’s disease Article Open access 14 December 2023 Introduction Schizophrenia (SCH) spectrum disorders are primarily diseases of the mind, affecting primarily mental, cognitive, emotional or behavioural...
All of these genes have been associ- ated with multiple sclerosis, Parkinson's, bipolar, ADHD or Alzheimer disease in at least one study (Anney et al 2008; Scott et al 2009). The results obtained from the CNV analy- sis in the 2p12 region indicated gains in two of the affected MDD...
they will need to be started as soon as the earliest changes occur in the disease, raising the question of what biomarkers to use to trigger treatment. Assuming that pericyte-mediated capillary constriction is indeed a very early event in the onset of AD (see Fig.3) as suggested by Iturri...
Early-onset dementia (EOD; < 66 years) is less common than late-onset dementia (LOD; > 65 years) [1]. In the majority of studies, Alzheimer’s disease (AD) is the most common subtype of EOD, followed by vascular dementia (VaD) and frontotemporal dementia (FTD) [2–4]. The cl...
The study focused on evaluating the outcome of ischemic heart disease (IHD), which encompassed angina (ICD-10 code I20) or acute myocardial infarction (ICD-10 code I21) occurring after the participants’ initial enrolment in the study. To establish baseline and follow-up survey outcomes, we co...
There is preliminary evidence that the age of onset of juvenile AN decreased during the last decade. Steinhausen and Jensen [10] reported that, in 2010, the most frequent age of onset ranged from 12 to 15 years, while the peak age of onset in 1995 was between 16 and 19 years. In the...
In a retrospective sub-analysis of a multicenter, prospective cohort study, Kushimoto and colleagues investigated the impact of blood glucose abnormalities on outcome and disease severity in patients with severe sepsis. They found that hypoglycemia was related to increased severity and high mortality in...
Characterization of a presymptomatic stage in a Drosophila Parkinson's disease model: Unveiling dopaminergic compensatory mechanisms. Biochim. Biophys. Acta-Mol. Basis Dis. 2017, 1863, 2882–2890. [CrossRef] Cells 2022, 11, 1544 15 of 16 21. Hidalgo, S.; Castro, C.; Zárate, R.V.; ...