Pathologically proven Alzheimer's disease (AD) manifest clinically with a broad spectrum of cognitive presentations beyond the classic progressive amnestic鈥恜redominant syndrome pointing to different patterns of selective vulnerability to AD pathology. As atypical clinical variants of AD tend to show a ...
Early-onset Alzheimer’s disease, also known as younger-onset, is the development of Alzheimer’s symptoms between the ages of 30 and 65. A diagnosis is relatively rare at a younger age, and while over 6 million people in the United States are living with Alzheimer...
Brain computed tomographic scans of 60 patients with early-onset Alzheimer's disease (mean age, 60.7 years) were compared with those of age- and sex-matched control subjects. Computed tomographic analysis included standard ventricular measurements as well as subjective ratings of ventricular and sulcal...
Early-onset Alzheimer's disease (EOAD) is a disorder with a dominantly inherited form, listed as being of significance for insurance by the Association of British Insurers. Mutations in the Presenilin-1 (PSEN-1) gene are responsible for a large proportion of cases. Gui & Macdonald (2002) ...
Early-onset Alzheimer’s disease, also called younger onset Alzheimer’s disease, is an uncommon form of dementia which affects individuals younger than the age of 65.
Alzheimer's disease (AD) is a progressive neurodegenerative disorder of the brain that ultimately results in the death of neurons and dementia. The prevalence of the disease in the world is increasing rapidly. In recent years, many studies have been done to automatically detect this disease from...
Spalletta G, De Luca V, Padovani A, Rozzini L, Perri R, Bruni A, Canonico V, Trequattrini A, Bellelli G, Pettenati C, Pazzelli F, Caltagirone C, Orfei MD (2013) Early onset versus late onset in Alzheimer's disease: what is the reliable cut-off? Adv Alzheimer Dis 2:40-47...
Follow-up observations were made of 92 white patients with early-onset Alzheimer's disease to determine the demographic, clinical, and neuropsychological factors predictive of institutionalization or death. The cumulative mortality rate 5 years after entry into the study was 23.9%, compared with an ex...
摘要: Background:Cognitive function in patients with Alzheimer type dementia (ATD) changes over time, and the rate of progression varies according to reports. An aim of the study is to examine the rate of progression in patients with ATD by the onset of the disease....
Early-onset Alzheimer's causes and risk factors According to theMayo Clinic, experts don't completely understand why some people have the disease at an early age. A genetic mutation in a small number of patients with early-onset Alzheimer's disease points to a cause. But in others, the rea...