Sepsis, a syndrome of acute organ dysfunction secondary to a systemic infection, has been recognized as a growing burden on healthcare systems and is responsible for nearly $24 billion annually. Various early sepsis detection scores have been developed to quantify the risk of clinical deterioration....
In hospitals in England, patients' vital signs are monitored and summarized into the National Early Warning Score (NEWS); this score is more accurate than the Quick Sepsis-related Organ Failure Assessment (qSOFA) score at identifying patients with sepsis. We investigated the extent to which the ...
In validation set, the AUCs of ANN, logistic regression, APAHCEII score, and SOFA score were 0.811, 0.752, 0.607, and 0.628, respectively. Conclusion: An ANN model for predicting 30-day mortality in sepsis was performed. Our predictive model can be beneficial for early detection of ...
Early diagnosis and treatment are crucial to prevent further deterioration of kidney function and the occurrence of systemic complications (such as sepsis). With the continual advancement of computer technology, radiomics has been widely applied in the diagnosis, differential diagnosis, and prognosis ...
More complex early-warning systems have not convincingly demonstrated that they are useful for the early detection of the deteriorating patient. When applied in an ideal mathematical way, these types of scores have reasonable sensitivity and specificity.13 However, in clinical practice, there are major...
EOS neonates sepsis therapy What is known? What is new? What is significant for clinical practice? 1. Introduction 1.1. Background/rationale Sepsis is a major cause of mortality and morbidity in neonates.1 It accounts for more than 20% of overall cause of neonatal death worldwide.1 Neonatal...
Early detection and response to patient deterioration are critical to avoid adverse events, preventable morbidity, cardiac arrest, unexpected ICU admission, and mortality [1]. Patients often display indicators of clinical deterioration up to 24 h before a significant clinical event arises needing extensiv...
This cohort study evaluates the association of implementation of the Severe Sepsis and Septic Shock Early Management Bundle (SEP-1) with sepsis treatment
(SOFA) score as part of the clinical criteria to identify and characterise sepsis [2], rather than an emphasis on the non-specific systemic inflammatory response syndrome (SIRS) [4], has proven controversial due to the complex nature of the score. The alternative quick SOFA (qSOFA) score ...
In another example, a recent systematic review compiled and compared the use of four predictive tools for sepsis diagnosis and adverse outcomes, showing the importance of such tools for effective resource allocation and earlier interventions [17]. The four tools summarized and compared were the ...