Byline: Fiona MacRae Science CorrespondentDaily Mail (London)
Drawing on a commonly used cognitive screening test, the Addenbrooke's Cognitive Examination-III (ACE-III), Dr. David Foxe led the development of the ACE-III PPA diagnostic calculator. Based onpatient datafrom the University's FRONTIER Research Group (dementia research), to which Dr. Foxe belon...
ould Be Screened]]>Byline: Fiona MacRae Science ReporterDaily Mail (London)
Aim: The aim of this study was to evaluate the reliability and validity of A Quick Test of Cognitive Speed (AQT) for detecting early-stage dementia in the elderly Japanese population.Methods: A total of 280 clinical participants (180 with mild Alzheimer's disease, 43 with amnestic mild cogni...
Such a strategy was recently successfully applied to patients with early-onset dementia,5 where a good sensitivity and a good specificity were found. The identification of previously unidentified causal variants in 2/10 samples previously sent for Sanger sequencing of one or more dementia genes ...
TR is partly supported by the National Institute for Health Research (NIHR) Queen Square Biomedical Research Unit in Dementia based at University College London Hospitals (UCLH), University College London (UCL). WH and KM conduct research at Great Ormond Street Hospital NHS Foundation Trust ...
et al. Caffeine consumption prevents memory impairment, neuronal damage, and adenosine A2A receptors upregulation in the hippocampus of a rat model of sporadic dementia. J. Alzheimers Dis. 34, 509–518 (2013). 29. Tebano, M. T. et al. Adenosine A2A receptors and metabotropic glutamate 5 ...
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developed a test that could detect clumps of amyloid-beta in the bloodstream. It could distinguish these clumps from other types of amyloid that aren’t thought to harm the brain. The test proved better at predicting the later development of Alzheimer’s dementia than other more invasive tests....
Adiposity and the risk of dementia: mediating effects from inflammation and lipid levels. Eur J Epidemiol. 2022;37(12):1261–71. Article CAS PubMed PubMed Central Google Scholar Russell B, Hemelrijck MV, Gårdmark T, Holmberg L, Kumar P, Bellavia A, Häggström C. A mediation ...