Here, we show inDrosophilathat MetR in early adulthood can extend organismal lifespan while MetR in later life is ineffective to do so. Using tissue-specific and single-cell RNAseq analyses, we delineate how the early-adult MetR impacts the transcriptome and tissue homoeostasis. Lifespan extensio...
Zinc deficiency during pregnancy and postnatal life can adversely increase risk of developing human diseases at adulthood. The present study was designed to evaluate whether dietary zinc deficiency or supplementation during the pregnancy, lactation and juvenile stages interferes in the development of mammary...
Dietary Switch from High Fat Diet to Normal Diet During Early Adulthood Does Not Restore Sperm Quality But Prevents Onset of the Metabolic SyndromeHigh-fat dietdietary switchmetabolomicsmale fertilityspermatogenesisBackground: Herein we postulated that high-fat diet (HFD) alters sperm quality and ...
Here, we show inDrosophilathat MetR in early adulthood can extend organismal lifespan while MetR in later life is ineffective to do so. Using tissue-specific and single-cell RNAseq analyses, we delineate how the early-adult MetR impacts the transcriptome and tissue homoeostasis. Lifespan extensio...
Zheng, M. et al. Breastfeeding and the longitudinal changes of body mass index in childhood and adulthood: a systematic review.Adv. Nutr.15, 100152 (2024). ArticlePubMedGoogle Scholar Zheng, M. et al. Early infant feeding and BMI trajectories in the first 5 years of life.Obesity28, 339...
On the other hand, in cross-sectional analyses at age 17 years, participants may have been more likely to follow the diet of their family or carers rather than their own individual dietary choices (which might emerge to a greater extent in early adulthood). It is unlikely that PUFA status ...
A number of social, behavioral, and environ-mental factors during early adulthood inuence cancer risk, including dietary patterns, physical inactivity, medical conditions (e.g., obesity, diabetes, viral infections), circadian rhythm disruption, chronic stress, and targeted marketing of cancer-causing ...
there is growing evidence that in utero InAs exposure is associated with increased frequency and severity of respiratory tract infections; in childhood, evidence of respiratory symptoms also begin to appear; and in adulthood, there is consistent evidence that InAs exposure is associated with deficits ...
In the early and mid-twentieth century, these long held beliefs about childhood’s capacity for intrusion into the experiences of adult life began to find their way into the borderlands of emerging science. Freud famously asserted that neurotic behavior and obsessions manifesting in mid-adulthood wer...
Another dietary modification observed in gravidae is the relative increase in fat intake during pregnancy. Studies of the effect of maternal high-fat diet consumption on offspring health have been conducted in multiple animal models. For example, in non-human primates exposed to maternal high-fat ...