This membrane-bound, respiratory complex also contains one non-covalently bound FAD, one non-covalently bound riboflavin, ubiquinone-8 and a [2Fe–2S] cluster. Here, we report the quantitative analysis of the full set of flavin cofactors in the Na+-NQR and characterize the mode of linkage ...
The SARS coronavirus envelope protein E contains a Class II PBM (-DLLVCOOH) that mediates the interaction of the protein with PALS1, affecting tight junction formation in infected cells (Teoh et al., 2010). Our results show that unlike the HAdV-C-specific E3-CR1β/ADP (Tollefson et al...
In conclusion, the YidC dimer contains two functional protomers although they can have some restrictive influence on each other. Each protomer is capable to bind one substrate protein and catalyses its membrane insertion. Methods Bacterial strains and plasmids YidC depletion was carried out using...
We found that ETS2 could weakly associate within vitro synthesized ETS1, c-Fos, and c-Jun and strongly with c-Fos/c-Jun complex and ERG via several distinct ETS2 domains including the C-terminal region that contains the DNA-binding domain. Strikingly, these interactions were stabilized in ...
Ras promotes robust survival of many cell systems by activating the phosphatidylinositol 3-kinase (PI3-kinase)/Akt pathway, but little is understood about the survival functions of the Ras/ERK pathway. We have used three different effector-loop mutant forms of Ras, each of which activates a ...
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