NERVOUS systemMYASTHENIA gravisTAU proteinsBackground: COVID-19 is a heterogenous disease resulting in long-term sequela in predisposed individuals. It is not uncommon that recovering patients endure non-respiratory ill-defined manifestations, including anosmia, and neurological and ...
CREB, in particular, plays a key role in nervous system development, cell survival, plasticity, and learning and memory.doi:10.1002/alz.12092Kwangsik NhoKelly NudelmanMariet AllenAngela Hodgesfor the Alzheimer's Disease Neuroimaging Initiative...
In the serotonin pathway, approximately 3% of TRP is metabolized by tryptophan hydroxylase (TPH) to 5-hydroxytryptophan and converted into 5-HT [16]. During the induction and development of MetS, 5-HT is produced in the brain (hypothalamus and striatum) and peripheral system (plasma and urine)...
Inflammationarkers (interleukin-6,-reactive protein,umor necrosisactor-alpha),ypothalamic-pituitary-adrenal-axis indicators (salivaryortisolwakeningurve [areanderheurve indicators, withespectohe groundnd increase], evening levels, 0.5g dexamethasoneortisoluppressionatio),ndutonomic nervousystemeasures (...
Abnormalities in the generation of the emotional response itself, potentially distinct from antecedents and control factors, have been implicated, including autonomic nervous system, endocrine, and reward sensitivity functions. In the context of emotion, there is less understood about the types of closed...
mRNA and protein of BCL2 exist at relatively high levels during the nervous system development, and decrease in the postnatal brain30,31,32. Abnormalities of apoptosis constitutes a pathogenesis of neurodevelopmental disorders33. The majority of neuronal cells are immature or premature in ...
e, All peptides mapping to the peripheral nervous system (PNS) isoform of MAPT. Colored bars indicate directional correlation for non-phosphorylated peptides. Red = correlated, blue = anti-correlated, grey = uncorrelated, light-grey = only phosphopeptides were seen in that region. Colored circles...
In addition to the HPA-axis, the CNS exerts its effects on the gut through branches of the ANS. All divisions of the ANS innervate the GI tract, including the parasympathetic nervous system, sympathetic nervous system as well as the intrinsic ENS [72]. The bidirectional brain-gut axis serves...
Dysregulation of genes with known functions as neurotransmitters in synaptic vesicles (SLC1A6 and VAMP1) and cell adhesion (PECAM1, CDH13 and SPG7) are related to diseases in the central nervous system. Dysregulation of these genes might reduce synaptic communication, and jeopardize cell-to-cell...
Emerging biological roles for erythropoietin in the nervous system. Nat Rev Neurosci. 2005;6:484–94. Article CAS PubMed Google Scholar Hormozdiari F, Penn O, Borenstein E, Eichler EE. The discovery of integrated gene networks for autism and related disorders. Genome Res. 2015;25:142–54....