Dysregulated moodDisordered thoughtManiaStory completionBipolar disorderThought disorderThere is rising interest in identifying precursors to bipolar disorder symptoms, including thought disorder. Thought disorder is identified in adults through self-report and in school-aged children through parent report and ...
Bipolar disorder and the gut microbiome: a systematic review. Bipolar Disord. 2021:23;544–64. Huang T-T, Lai J-B, Du Y-L, Xu Y, Ruan L-M, Hu S-H. Current understanding of gut microbiota in mood disorders: an update of human studies. Front Genet. 2019;10:98. CAS PubMed Pub...
While the psychiatric symptoms of schizophrenia can be managed by current antipsychotic medications, there is room for improvement in the management of other aspects of the disorder, such as the cognitive deficits and significantly reduced lifespan seen in persons with schizophrenia. Despite the presence...
Adolescence is an unrelenting succession of highs and lows. The swings between euphoria and misery, jealousy and generosity, irritation and vulnerability come quick and hard — and often. For teens with attention deficit hyperactivity disorder (ADHD) and its relatively common partner, emotional dysregul...
Influence of tryptophan and serotonin on mood and cognition with a possible role of the gut-brain axis. Nutrients. 2016;8(1):56. Article PubMed PubMed Central Google Scholar Mittal R, Debs LH, Patel AP, Nguyen D, Patel K, O’Connor G, et al. Neurotransmitters: the critical modulators...
Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder of heterogeneous nature. Secreted frizzled-related protein (SFRP) 5 is an anti-inflammatory adipokine implicated in metabolic homeostasis. We aimed to confirm the correlation between SFRP5, metabolic inflammation and PCOS, investigate the...
In addition to regulating hepatic metabolism, FXR has a role in altering motor activity, cognitive function, and mood [10]. FXR agonist is currently in clinical trials to treat metabolic liver diseases [61]. Whether FXR agonists can be used to improve neuroplasticity warrants further investigation...
An approach to the patient with dysregulated mood: major depression and bipolar disorder.[J].The Medical Clinics of North America 2010,6(6).Querques, J. Kontos, N. An approach to the patient with dysregulated mood: major depression and bipolar disorder. Medical Clinics of North America, 2010...
Novel mechanistic concepts of the neurobiology of depression and bipolar disorder are evolving based on recent pre-clinical and clinical studies. Ongoing research could lead not only to a breakthrough in identifying the causative factors associated with mood disorders but also to the development of ...
Moreover, hyperresponsivity to stressors correlates with depressed mood and may contribute to the etiology of major depression. The serotonergic dorsal raphe nucleus (DRN) is an important site in the neurocircuitry underlying behavioral responses to stressors, and is tightly regulated, in part, by ...