The meaning of DYSREGULATION is impairment of a physiological regulatory mechanism (as that governing metabolism, immune response, or organ function).
Two moments from the clinical narrative under discussion are used to highlight the critical impact of attention to timing not in terms of when and what to say, but rather as a an ongoing source of emotional meaning emerging on implicit dimensions of rhythm and affective tone occurring in the ...
However, different emphases across – and within – subfields produce differences in its meaning. Summarizing its prevailing uses will provide grounding for this review of the processes that might underlie its phenomenology. Perhaps the leading use of emotional dysregulation pertains to emotion regulation...
Long non-coding RNAs (LncRNAs) Only 2% of the human genome accounts for protein-coding regions, yet more than 70% of the human genome is transcribed in RNA that does not encode proteins [20]. Whether the entirety of the cellular transcriptional output has a functional role is still unknown,...
The inverse pairs are the canonical understanding of miRNA:mRNA interactions, meaning that as the expression of one changes, it is expected that the expression of the other will change in the opposite direction. The coordinately expressed pairs can represent either false-positive predictions or ...
However, the 10 exon form noted above appears to split the last exon into two small exons, meaning a frameshift stop could have the potential to be in the last but one exon and hence caught by NMD. Authors’ response: The canonical splice form would still be expected to be resistant to...
DAVID bioinformatics resources consists of an integrated biological knowledgebase and analytic tools aimed at systematically extracting biological meaning from large gene/protein lists. This protocol explains how to use DAVID, a high-throughput and integrated data-mining environment, to analyze gene lists ...
Prenatal environment significantly influences mammalian fetal development and adverse in utero conditions have life-long consequences for the offspring hea
The use of the word “a” or “an” when used in conjunction with the term “comprising” in the claims and/or the specification may mean “one,” but it is also consistent with the meaning of “one or more,”“at least one,” and “one or more than one.” The use of the term...
However, long-term plasticity is homosynaptic, meaning that synaptic strength is selectively enhanced in those synapses receiving repetitive stimuli, whereas in central sensitization, both activated synapses and non-activated neighboring synapses are enhanced. In addition, continuous long-term plasticity ...