Dyskeratosis congenita (DKC) is an inherited disorder that usually presents in males, consisting of the triad of leukoplakia of the mucous membranes, nails dystrophy and skin pigmentation. Oral and dental abnormalities may also be present. Most cases are X-linked autosomal dominant, but recessive ...
Dyskeratosis congenita is a rare congenital disorder affecting mainly the integumentary system. It is a progressive disease with involvement of bone marrow. A triad of hyperpigmentation, nail dystrophy and leucoplakia are characteristic of this disease. DOI: http://dx.doi.org/10.3126/jnps.v33i...
Dyskeratosis CongenitaHematopoietic Stem Cell TransplantationHumansImmunosuppressionTelomere骨髓疾病角化不良先天性造血干细胞移植Excerpt DISEASE CHARACTERISTICS: Dyskeratosis congenita (DC), a telomere biology disorder, is characterized by a classic triad of dysplastic nails, lacy reticular pigmentation of the upper...
Dyskeratosis congenita (DC) is an inherited bone marrow failure syndrome characterized clinically by the triad of abnormal nails, reticular skin pigmentation, and oral leukoplakia, and is associated with high risk of developing aplastic anemia, myelodysplastic syndrome, leukemia, and solid tumors. Patient...
Dyskeratosis congenita (DKC) is a rare inherited disease characterized by the triad of abnormal skin pigmentation, nail dystrophy, and mucosal leukoplakia. 先天性角化 (DKC)为一少见之遗传性疾病,三项主要特徵为皮肤色素 常、 指甲生长 常及黏膜白斑 ...
Dyskeratosis congenita (DC) is an X-linked recessive trait which is characterized by bone marrow failure and a triad of mucosal leukoplakia, nail dystrophy, and abnormal skin pigmentation [12, 30–32]. From: Hematopathology, 2008 Related terms: ...
Dyskeratosis congenita DC is a severe inherited BM failure syndrome that is characterised by a triad of mucocutaneous features: abnormal skin pigmentation, leucoplakia and nail dystrophy, as well as by a variety of somatic features (Table 1). This disease is clinically and genetically heterogeneous...
1.Dyskeratosis congenita (DKC) is a rare inherited disease characterized by the triad of abnormal skin pigmentation, nail dystrophy, and mucosal leukoplakia. 先天性角化不(DKC)一少见之遗传性疾病,三项主要特徵皮肤色素常、 指甲长常及黏膜白斑。 声明:以上例句、词性分类均由互联网资源自动,分未经过人工审...
Dyskeratosis congenita is a syndrome of bone marrow failure secondary to unstable telomeres. It is characterized by a range of mucocutaneous diseases. Due to premature telomere shortening, these patients have limbal stem cell deficiency leading to poor regeneration and maintenance of the cornea. Many ...
Dyskeratosis congenita (DC) is a multisystem bone marrow failure syndrome characterized by a triad of mucocutaneous abnormalities and a predisposition to c... AJ Walne,T Vulliamy,R Beswick,... - 《Blood》 被引量: 1091发表: 2008年 Disease anticipation is associated with progressive telomere shorten...