(2017). DNA-RNA hybrids: The risks of DNA breakage during transcription. Nat. Struct. Mol. Biol. 24, 439-443.Aguilera, A. & Gomez-Gonzalez, B. DNA-RNA hybrids: the risks of DNA breakage during transcription. Nat
During transcription the direction in which RNA polymerase slide along DNA template is ( ).A. 5′ → 3′B. N-terminal → C-terminalC. 3′ → 5′D. C-terminal → N-terminalRNA聚合酶沿DNA模板的幻灯片是在哪个方向()。A. 5'→3'...
Transcription of Messenger RNA (mRNA) from DNA? Transcription is the process of synthesizing RNA which is controlled through interactions of promoters and enhancers. During this process multiple types of RNA are produced, such as mRNA, tRNA, and rRNA. ...
DNA methylation is an essential component of transposable element (TE) silencing, yet the mechanism by which methylation causes transcriptional repression remains poorly understood1–5. Here we study the Arabidopsis thaliana Methyl-CpG Binding Domain (MB
This engagement process involves the following steps (Figure 1B) (reviewed in Roberts et al., 1998). RNAP initiates transcription at PR′ and pauses after synthesizing a transcript of 16 or 17 nucleotides. This is enough to clear the promoter, allowing λQ to bind the QBE. DNA-bound λQ...
aTik ToK 正在翻译,请等待...[translate] a지금 우리회사에 正在翻译,请等待...[translate] aHow is mRNA processed? 正在翻译,请等待...[translate] aThe mRNA code that is made during transcription has all of the DNA code. 正在翻译,请等待...[translate]...
We have studied the transcription of the CTP:phosphocholine cytidylyltransferase α (CTα) gene in C3H10T1/2 fibroblasts as a function of the cell cycle. The cells were incubated for 48 h with 0.5% fetal bovine serum. The cells were induced into the G1 phase of the cell cycle by the ...
Alternative splicing (AS) is a principal mode of genetic regulation and one of the most widely used mechanisms to generate structurally and functionally distinct mRNA and protein variants. Dysregulation of AS may result in aberrant transcription and protein products, leading to the emergence of human...
. However, despite the availability of the complete sequence of thePlasmodium falciparumgenome, we are still quite ignorant aboutPlasmodiummechanisms of transcriptional gene regulation. This is due to the poor prediction of nuclear proteins, cognate DNA motifs and structures involved in transcription....
However, replisomes in cellular environments encounter numerous challenges, including transcription complexes, DNA lesions, and constant nucleotide mismatches, which potentially disrupt the stability and defined structure of the replisome4,5. Contrary to that conventional model, recent evidence from single-...