in terms of the competition between elastic properties of fusing systems driving to the re-separation of colliding nuclei and the dissipative (plastic) properties of nuclear matter transforming the energy of collective motion into the energy of statistical excitation and thus leading to the fusion. Th...
Reports that Fus2 localizes near the site of cell fusion and is required for both cell fusion and nuclear alignment during zygote formation. Sequence of th... Elion,Elaine,A.,... - 《Journal of Cell Biology》 被引量: 114发表: 1995年 The function and regulation of Fus2p during cell fus...
Our data reveal a positive correlation between m6A modifications and gene expression homeostasis across tissues as well as tissue-type-specific aging-associated m6A dynamics. Among these tissues, skeletal muscle is the most susceptible to m6A loss in aging and shows a reduction in the m6A ...
As oxygen vacancies can be generated more easily at high undercoolings, it is reasonable to attribute the color change to a phase transition rather than the disappearance of oxygen vacancies. In order to verify the hypothesis, five representative samples solidified under different undercoolings were ...
is present. We considered a metagene as present in a cell if at least 25% of all associated genes had at least one UMI count.DFor each metagene and T-cell population that was significant (p < 0.05) in the Wilcoxon rank-sum test, we generated a null distribution in order to ...
The C terminus of apoA-II was required for the proper chromosome separation during nuclear division of YSL in zebrafish embryos and in human HeLa cells. Our data indicate that organization of YSL is required for blastoderm patterning and morphogenesis and suggest that apolipoprotein apoA-II is a ...
The activation of host’s innate and adaptive immune systems can lead to acute and chronic graft rejection, which seriously impacts graft survival. Thus, it is particularly significant to clarify the immune signals, which are critical to the initiation and maintenance of rejection generated after tra...
Due to the unique nature of spermatozoa, which are transcriptionally and translationally silent, the regulation of capacitation is based on the formation of posttranslational modifications of proteins (PTMs). However, the interactions between different t
To specifically monitor Fgf/Erk signaling dynamics in vivo, we generated an improved Erk biosensor devoid of Cdk1 responsiveness (modErk-KTR). To achieve this, we introduced an R>A substitution within a putative cyclin-docking site (RxLxΦ, where Φ is a hydrophobic residue) in the Erk-dock...
Thus, BNIP3L supports mitophagic flux in both cortical-like and DA-type neurons generated from hESCs. LIR motif is required for BNIP3L-dependent mitophagy in iNeurons As a MOM protein, BNIP3L is in the proper location to direct mitophagy through recruitment of relevant factors. Previous ...