aDuring interphase, eukaryotic chromosomes are uncondensed and looped, with the ends of the loops attached to the nuclear matrix(see chapter 1) 在相界面, eukaryotic染色体期间是uncondensed和使成环,与圈的末端附有核矩阵(看第1章)[translate]
Amenta, PS, Gersh, I, Gersh, E Persistence of individuality of chromosomes during interphase, and the role of the nuclear membrane. In: Gersh, I eds. (1973) Submicroscopic cytochemistry. 1. Proteins and nucleic acids, vol 1. Academic Press, New York, pp. 365-375...
If a cell has 4 chromosomes during interphase, how many chromosomes will each new cell have? If there was a nondisjunction during meiosis I that prevented one pair of homologous chromosomes from separating, how many chromosomes would each gamete have? Draw them. ...
For instance, we and others recently discovered that interphase chromosomes are partitioned into megabase-sized topological domains and smaller sub-domains (also known as topologically associated domains or TADs)6,7,8,9. These TADs form the basis for higher-level structures referred to as the ‘A...
2a). Indeed, co-staining with the Mt-plus-end binding protein EB1 showed that GFP-KLHL21 accumulated at Mt tips in over 90% of Mts reaching the cortex in interphase (Supplementary Fig. 2A, over 150 EB1 comets). Accumulation of KLHL21 at Mt-plus ends required EB1, as GFP-KLHL21 ...
a human will have 46 chromosomes, but 92 chromatids (again, remember that there are 92 chromatids because the original 46 chromosomes were duplicated during S phase of interphase). It is helpful to see this visualized (for visual simplicity, a 2n=8 arrangement of chromosomes will be demonstrat...
Cellularisation occurs during the interphase of 14th nuclear division. During this stage the actin filaments in mof1 embryos loose the typical honeycomb like structures often leading to empty cages without the chromosomes. The empty cages are indicative of the presence of abnormal nuclei that are ...
Meiosis I is quite similar to mitosis.However,there are a number of crucial differences between meiosis I and mitosis,all of which will be outlined in the discussion of each individual stage below.Interphase IJust as in mitosis,the cell undergoes DNA replication during this intermediate phase....
While chromothripsis typically involves multiple focal deletions in a single chromosome (thought to occur during metaphase)20,21, chromoplexy is defined as a series of inter-dependent rearrangements among multiple chromosomes (most likely during interphase)19. Although we did not find evidence of ...
assessed by qRT–PCR in control (empty bars) and bound (empty bars, lighter shade) PGK12.1 XXTetO TetR-EGFP cells (*P < 0.05, **P < 0.01, t-test (unpaired, two-tailed); error bars indicate s.d.; n = 3; individual data points are depicted next to the respective bar...