To evaluate the usefulness of serum DU-PAN 2 (an antigen defined by a monoclonal antibody raised against human pancreatic carcinoma cells), serum specimens from 370 cases of hepatobiliary and pancreatic diseases along with 31 normal controls were studied using an enzyme immunoassay. Elevated levels ...
This work describes the molecular properties of a human pancreatic adenocarcinoma-associated mucin-like antigen defined by a murine monoclonal antibody (DU-PAN-2). DU-PAN-2 antigen is a large molecule, readily detected in the body fluids... MS Lan,OJ Finn,PD Fernsten,... - 《Cancer Researc...
Molecular mechanism of reversal effect of monoclonal antibody to basic fibroblast growth factor-mediated expression of P-glycoprotein on multiple drug resi... Objective:To investigate the mechanism of reversal effect of bFGF mAb (monoclonal antibody to basic fibroblast growth factor)-mediated expression ...
and Fukui, M., Measurement of a pancreatic cancer-associated antigen (DU-PAN-2) detected by a monoclonal antibody in sera of patients with digestive cancers, Int. J. Cancer, 1986; 37: 693–696. Article PubMed CAS Google Scholar Koprowski, H., Steplewski, Z., Mitchell, K., Herlyn,...
N-(2-Aminoethyl)-2-(naphthalen-1-yl)acetamide-d4 | MedChemExpress (MCE) 面议 Lanthanum(Ⅲ) chloride | MedChemExpress (MCE) ￥110~160 Eltrekibart | MedChemExpress (MCE) 面议 Anti-Integrin a11/ITAG11 Antibody | MedChemExpress (MCE) 面议 Octreotide | MedChemExpress (MCE) ￥500...
DIAGNOSIS OF PANCREATIC CANCER USING DUPAN - 2 MONOCLONAL ANTIBODYOpocher, E.Spina, G. P.Santambrogio, R.Cucchiaro, G.Vignati, L.Tarolo, G. L.Marelli, F.Borzio, F.Pedersoli, P.HPB Surgery
Levels of a new carbohydrate antigen CA 19-9, which is a monosialoganglioside identified by a monoclonal antibody raised against colorectal carcinoma cells... P Piantino,A Andriulli,T Gindro,... - 《American Journal of Gastroenterology》 被引量: 106发表: 1986年 Clinical value of serum tumor...
The antigen DU-PAN-2, recognized by a monoclonal antibody derived from a human pancreatic adenocarcinoma cell line by Metzger et al. in 1982 (19), has been utilized as a specific maker for tumors arising in the digestive tract (20–24). DU-PAN-2 (Sialyl-Lewisc) is the precursor...
To solve this problem, the present invention provides an antibody that specifically reacts with the sugar chain of DUPAN-2 antigen to be used as a tumor marker and a method for producing the antibody.MIURA TOMOHIROMIYAZAKI OSAMU
and it has been a drawback that tumor marker detection using such an antibody is low in detection specificity, thereby deteriorating accuracy of cancer diagnosis.To solve the object described above, the present invention provides an antibody specifically reactive with a glycan of DUPAN-2 antigen fo...