For most adults less than 65 years of age with GAD, initiate duloxetine delayed-release capsules 60 mg once daily. For some patients, it may be desirable to start at 30 mg once daily for 1 week, to allow patients to adjust to duloxetine delayed-release capsules before increasing to 60 mg...
Duloxetine was reinitiated at a dosage of 30 mg/day and, 2 hours later, she experienced a relapse of generalised rash along with development of a hoarse voice, dyspnoea and swelling of her tongue. She received IV hydrocortisone, corticosteroids and histamine H1 receptor antagonists and, within ...
However, 10 mg/kg doses did not significantly reduce the mechanical and cold allodynia elicited by oxaliplatin injection. Thus, 30 mg/kg of duloxetine was shown to be the optimal dose in this experiment, as 10 mg/kg showed weak analgesic effect, and despite its strong analgesic effect somno...
Administration of 30 and 60 mg/kg of duloxetine significantly reduced the allodynia, whereas 10 mg/kg did not. By using an in vivo extracellular recording method, we further confirmed that 30 mg/kg of duloxetine could significantly inhibit the hyperexcitability of spinal wide dynamic range (WDR)...