Development of biodefense strategies in order to control the effects and protect soldiers and civilians from biothreats is essential. This, however, leads to a problem of Dual-Use Research (DUR), since information on pathogenesis necessary for finding means of controlling infection, could ...
DUALUSERESEARCHOF CONCERN USGovernment(USG)PolicyforInstitutionalOversightofLifeSciences 10/13/2014 ReleaseDate:September24,2014 EffectiveDate:September24,2015 Policy“articulatesthepracticespracticesand proceduresproceduresrequiredtoensurethatdualuse researchofconcernisidentifiedatthe ...
El-Deeb1, Ralf Altmeyer2,3,†, Patrice Guillon1,† & Mark von Itzstein1,† Human parainfluenza type-3 virus (hPIV-3) is one of the principal aetiological agents of acute respiratory illness in infants worldwide and also shows high disease severity in the elderly and ...
Since the katAp2 transcription is abolished in the anr mutant, accounting for the basal expression of KatA dur- ing the may be planktonic associated growth, with the we have katAp2 ttreasntesdcriifptthioenAansrw-deelpl.eWndeehnatvNe Oex3p−loreitsepdirtahtieomn udtuarnintsgftohrethpelagne...
However, with the use of TRK inhibitors for about 3 years now, we have started to see development of resistance in these patients to first- line TRK inhibitors, and research is urgently needed to elucidate mechanism of resistance, especially in the NTRK2 fusion tumors, to develop better 2nd ...
While physician placement has grown in both the public and private sectors in recent years, further growth is necessary to address the unmet healthcare needs of the ageing population and to replace those who will soon retire. We hope that this research can provide insights into physicians' respon...
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Recovering motor func- tion after stroke might be conceptualized as learning to use the remaining neural resources to improve motor planning, execution, feedback, and control. Thus, motor recovery after stroke could be a form of motor skill learning. It is still unclear w...
We believe the synergism found to be at least in part the result of the simultaneous block of the CCNE1 and the PI3K pathways, two of the most frequently deregulated molecular pathways in USC (Kuhn et al, 2012; Cancer Genome Atlas Research Network et al, 2013; Zhao et al, 2013; Schwab...
The ideal choice of BC is the major goal of local flow-based upscaling research. The major examples of BC used include no-flow, periodic (Durlofsky 1991) as well as linear (King and Mansfield, 1999) boundary conditions each of which has its strengths. Generally, no-flow boundary condition...