3、宏蛋白组学分析揭示了DSS治疗后微生物群的功能变化 共鉴定盲肠内容物蛋白5603个,远端结肠内容物蛋白6390个,远端结肠粘液蛋白7102个。DSS处理显著影响蛋白质功能的丰富性。DSS处理对结肠粘液中碳代谢有显著影响。此外,氨基酸代谢(即色氨酸)和脂肪酸代谢显示出明显的变化,表明在结肠粘液相关微生物群的代谢中存在生理效应。
The purpose of the present study was to investigate the anti-inflammatory effects of a sugar isomer, leucrose (D-glucopyranosyl-α-(1–5)-D-fructopyranose) in a dextran sulfate sodium (DSS)-induced colitis mouse model and in RAW 264.7 macrophages. Colitis was induced in vivo with ...