At each time point, 5 mL of the medium was withdrawn and filtered through a 0.45 µm polytetrafluoroethylene PTFE filter discarding the first Pharmaceutics 2019, 11, 68 5 of 21 2–3 mL. A volume (1.5 mL) of the remaining sample was transferred in amber glass vials for further analysis...
The measurement length was 4 mm, with a probe travel speed of 0.5 mm/s, and the roughness tests were carried out according to standard UNI ISO 4288-2000 [26], a Gaussian filter with a 0.8 mm cut off was selected. The roughness tests were performed three times for each hole, along ...
2 Furnace Temperature Controller 1 PC MFC 01 MFC 04 Serpentine Vacuum Pump Buble Flow Meter Pd-Membrane Reactor LEGEND Feed Line Permeate Line Retentate Line Vent 3 BPC Serpentine Back Pressure Controller Gas Chromatography PC Filter to remove H2O Buble Flow Meter Figure 2. Sketch of the lab-...
Keywords: gas sorption porometry; liquid-liquid porometry; cryoporometry; mille-feuille filter, parvovirus; virus removal filter 1. Introduction Virus removal filtration is a robust method to clear viruses and other microbial pathogens from liquids during manufacturing of protein-based pharmaceuticals and ...