The article reports on an updated post-exposure prophylaxis (PEP) regimen proposed in draft guidelines by the Centers for Disease Control and Prevention (CDC) in June 2012. David Kuhar, medical officer with CDC's Di...
Anti-HIV-1 Activity of pepRF1, a Proteolysis-Resistant CXCR4 Antagonist Derived from Dengue Virus Capsid Protein There is an urgent need for the development of new anti-HIV drugs that can complement existing medicines to be used against resistant strains. Here, we rep... I Cadima-Couto,A ...
Can Biktarvy be used for PrEP or PEP? Biktarvy (bictegravir, tenofovir, and emtricitabine) is not FDA approved for use as an HIV-1 preventive for pre-exposure prophylaxis (PrEP) or as a post-exposure prophylaxis (PEP) treatment. Biktarvy is used for HIV treatment (not for prevention)...
Initiate PEP as soon as possible following occupational exposure to HIV (preferably within hours); continue for 4 weeks, if tolerated.Special PopulationsHepatic ImpairmentUnboosted atazanavir in treatment-naïve adults with mild hepatic impairment (Child-Pugh class A): 400 mg once daily....
Dear Dr David Wohl I have finished pep after having sex with an hiv+ prostitute(a girl). I used condoms through out but there was a cut on my winnie that could be from trauma during my private masturbation sessions. It was about 5 days old and clotte...
This guideline from the International Antiviral (formerly AIDS) Society–USA updates practice recommendations for managing HIV infection, including when to
Post-exposure prophylaxis (PEP) is an emergency Human Immunodeficiency Virus (HIV) prevention method where individuals start a 28-day course medication within 72 hours of HIV exposure in order to prevent an infection…. Read MoreWhen to Lose Your Virginity Defining “Losing Your Virginity” ...
Allosteric modulation of anti-HIV drug and ferric heme binding to human serum albumin. FEBS J 2005; 272: 6287–96. 85 Chen J, Hage DS. Quantitative studies of allosteric effects by biointeraction chromatography: analysis of protein binding for low- solubility drugs. Anal Chem 2006; 78: 2672...
Cautions for NevirapineContraindicationsModerate or severe hepatic impairment (Child-Pugh class B or C). Do not use for postexposure prophylaxis following occupational exposure to HIV (PEP) or for postexposure prophylaxis following nonoccupational exposure to HIV (nPEP)....
Postexposure prophylaxis of HIV infection following nonoccupational exposure† [off-label] (nPEP) in individuals exposed to blood, genital secretions, or other potentially infectious body fluids that might contain HIV when the exposure represents a substantial risk for HIV transmission....