Effects of anesthetics and drugs used during anesthesia on the pulmonary circulation - MK - 1986Sykes MK. Effects of anesthetics and drugs used during anes- thesia on the pulmonary circulation. In: Altura B, Halevy S, eds. Cardiovascular actions of anesthetics and drugs used in anesthesia. ...
DRUGSUSEDFORANESTHESIA,MUSCLERELA,ATION1DRUGSUSEDFORANESTHESIAMUSCLERELA,ATION用于麻醉的药物肌肉松弛A,LocalanesthesiaAsthenameimpli
For some basic lipophilic amines the high first pass uptake in the human lung controls the initial rate of entry of the major portion of the dose into the systemic circulation and plays a complex role in moderating plasma drug concentrations during the early distributional phase of plasma ...
These drugs are used during surgery (especially intra-abdominal and intrathoracic), and to aid intubation for surgical and diagnostic procedures (endoscopy). ? Previously, adequate muscle relaxation was only possible with deep anesthesia (which leads to CNS depressant effects). ? Contraction of ...
The pulmonary circulation is capable of a very rapid and extensive extraction of certain drugs from the blood during a single transit through the lung after intravenous administration of the drug bolus. The extent of uptake depends on the physicochemical characteristics of the drug and its binding ...
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Our data show that some drugs used during anesthesia exert changes in feeding behavior and this effect is associated with modulation of two interconnected populations of neurons (POMC and NPY) in hypothalamic ARC. One hypothesis that could explain these observations would be a direct hypothalamic stim...
In this study, we analyse the ability of certain drugs used during perioperative procedures and anaesthesia to induce MRGPRX2-dependent degranulation in human mast cells and sera from patients who experienced an anaphylactoid reaction during the perioperative procedure. Using a β-hexosaminidase release...
Drugs used for the induction, maintenance and reversal of anaesthesia carry the risk of adverse reactions. Adverse drug reactions (ADRs) include overdose, adverse and secondary effects, idiosyncratic reactions, drug intolerance and allergic reactions. Reports of severe ADRs in anaesthesia appear to be ...