摘要: This article reviews current knowledge of the metabolism of drugs that contain fluorine. The strategic value of fluorine substitution in drug design is discussed in terms of chemical structure and basic concepts in drug metabolism and drug toxicity.关键词:...
by having two intended uses (such as a shampoo that is also intended to treat dandruff, or toothpastes that contain fluoride, deodorants that are also antiperspirants, and moisturizers and makeup marketed with sun-protection claims). Such products must comply with the requirements for both cosmet...
bacteria contain fluorine atoms,even though around a fifth of all pharmaceutical products on the market contain at least one fluorine moiety.A major reason for the paucity of naturally-occurring tluorinated compounds is the low concentration of free fluoride ions in the environment compared with ...
Fungal sclerotium ofClaviceps purpureagrowing preferentially on rye (Secale cereale). It is assumed that farmers in Sologne, south of Paris, first called it ergot, because it is reminiscent of the spur of a rooster (fr.l'ergot de coq). An early written reference of the term “ergot” and...
reported that smoking MDMA may increase the risk of adverse effects. MDMA may contain “bath salts” or other additives, which can be potentially dangerous when smoked. Smoking a substance increases the risk of breathing problems, lung damage and infections. Although research on smoking MDMA is ex...
Inline filters: Polyethersulfone solution filter (PES), polyvinylidene fluoride air filter (PVDF). o Closed System Transfer devices: acrylonitrile-butadiene-styrene (ABS), acrylic c-polymer, polycarbonate (PC), polyisoprene (PI), polyester, polypropylene (PP) polytetrafluoroethylene (PTFE), silicone ...
Calcium and sodium are also common mineral medicine ingredients. Calcium-containing mineral medicines mainly contain oxides, carbonates, and calcium fluoride as their main active ingredients. Calcium-containing mineral drugs have a wide range of clinical applications in gynecological diseases. In addition,...
Administer by IV infusion over 30 minutes through an IV line containing a sterile, non-pyrogenic, low protein binding in-line polyethersulfone (PES), nylon, or polyvinylidene fluoride (PVDF) filter (pore size of 0.2–1.2 micrometer).1 Flush the IV line at the end of the infusion.1 Do ...
Multivitamins/Fluoride (with ADE): Multivitamins/fluoride (with ADE) may enhance the adverse/toxic effect of vitamin D analogues. Avoid combination. Multivitamin products with higher doses of vitamin D pose a higher risk than those products with smaller doses of vitamin D.(Calcijex 2004,Dovonex...
propolis.(Hwu 2014) Data from 19 twin pairs enrolled in a double-blind, randomized controlled equivalence trial showed propolis 2% mouth rinse resulted in a reduction in induced gingivitis similar to that with positive control (sodium fluoride with CPC rinse) after 21 days of treatment.(Bretz ...