Many drugs may cause systemic lupus erythematosusdoi:10.2165/00128415-199103530-00005&NA;Springer International PublishingReactions Weekly
Since it was first suggested that the onset of a syndrome closely resembling systematic lupus erythematosus (SLE) might be related to drug therapy at least 27 drugs have come under suspicion. These drugs are classified into 2 groups. The first one includes hydralazine, procainamide, diphenylhydantoi...
Systemic lupus erythematosusRandomized controlled trialspSystemic lupus erythematosus is the prototypic autoimmune disease with a broad range of clinical manifestations and a complex pathogenesis. B-cells hold a central role in its pathogenesis, not only as autoantibody producing cells, but also by ...
May cause damage to peripheral nerves, leading to weakness, numbness, and pain in the hands and feet. The addition of pyridoxine (vitamin B6) may help. Hydralazine is one of the most common drugs implicated in Drug-induced Systemic Lupus Erythematosus (DILE). Symptoms may occur anywhere from...
The Systemic Lupus Erythematosus pipeline market research report provides comprehensive information on the therapeutics under development for Systemic Lupus Erythematosus, complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA), and molecule type...
• Systemic lupus erythematosus: Use with caution in patients with systemic lupus erythematosus (SLE); may exacerbate disease. Women with SLE are at an increased risk for heart disease, stroke, and VTE. Combination hormonal contraceptives should not be used in women with SLE who have positive ...
求翻译:Systemic Lupus Erythematosus --Developing Drugs for Treatment是什么意思?待解决 悬赏分:1 - 离问题结束还有 Systemic Lupus Erythematosus --Developing Drugs for Treatment问题补充:匿名 2013-05-23 12:21:38 系统性红斑狼疮--Developing药物进行治疗 匿名 2013-05-23 12:23:18 系统性红斑狼疮--...
In systemic lupus erythematosus (SLE), a drug might (a) exacerbate underlying idiopathic SLE, (b) induce SLE in a predisposed patient, or (c) cause the distinct syndrome of drug-induced lupus (DIL). Causality of potential inciting agents is hard to prove, with many associations based upon ...
The metabolism of Pegasys is not fully characterised; however studies in rats indicate that the kidney is a major organ for excretion of radiolabelled material. In humans, the systemic clearance of peginterferon alfa-2a is about 100-fold lower than that of the native interferon alfa-2a. Afte...
Usual Adult Dose for Systemic Lupus ErythematosusDosing should be individualized based on disease and patient response: Initial dose: 5 to 60 mg orally per day Maintenance dose: Adjust or maintain initial dose until a satisfactory response is obtained; then, gradually in small decrements at ...