An alginate-pectin-polylysine combination has shown promise as a vehicle for controlled-release medications. The presence of a rigid pectin gel inside the particulates imparts a stronger and more stable vehicle in acidic and alkaline solutions, which could prolong drug release. This particulate system...
If administered rectally† [off-label], insert the dosage form just inside the rectal sphincter for optimal systemic absorption of unmetabolized drug. Administration high in the rectal vault can result in rapid first-pass hepatic metabolism, with greatly diminished efficacy....
Dave Evans, founder, Austin Area Multimedia Alliance (now VP of social strategy, Lithium Technologies): You know people who are that balance between genius and energy? Everything is going fine, going fine, going fine, and inside they’re just tearing themselves apart? Every time you saw Dewey...
Through the expansion of the genetic code (Wang et al., 2001, Wang and Schultz, 2004, Wang, 2017a), we introduce into the protein drug a latent bioreactive unnatural amino acid (Uaa), which has latent chemical reactivity and remains inert inside the protein and in vivo. Upon binding of...
Dif- ferent concentrations inside the working range of each drug were prepared and the previously explained method in "Calibration graphs construction" section was followed. The content of each drug in the prepared dosage form was calculated using the corresponding regression equation. Analysis of the...
Mice were placed in isolation chambers inside closed Plexiglas tubes outfitted with accelerometers. Following a 5-min habituation period with 74 dB back- ground white noise, each animal received 40 randomized trials separated by 20–30 s. Trials consisted of 10 each background readings taken at ...
CADs have the ability to accumulate inside cells affecting several structures/functions hijacked by viruses during infection. In their review, Salata and co-workers (2017) summarized the CADs' chemical properties and effects on the cells and reported the main FDA-approved CADs that have been ...
increased pressure inside the skull - severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes.Common Accutane side effects may include:dryness of your skin, lips, eyes, or nose (you may have nosebleeds); vision problems; headache, back pain, joint...
Place the tip of the syringe along the inside of your child’s cheek. Slowly push the plunger all the way in to give the entire dose. Repeat with second syringe if needed to complete the prescribed dose. Note: this medication must be given as soon as possible after being drawn from the...
Inside Windsor’s Olde Walkervillepharmacy, where traditional brown medicine bottles line the shelves, 30-year-old Stephanie Odette from Michigan tells Sanders how it felt when she rationed insulin. “It’s like the world’s worst hangover. Except you didn’t drink anything,” she half-laughs....