There is a high degree of interindividual variability in the plasma concentration profile of telmisartan. As a result of saturable first-pass metabolism, the oral bioavailability of telmisartan is dose dependent (42.4% after a single 40mg oral dose) and maximum plasma concentrations (Cmax) increase ...
Clinical trials showed that intravenous trabectedin was effective in chemotherapy-experienced patients with advanced, recurrent liposarcoma or leiomyosarcoma, and results from a retrospective analysis suggest that the drug may be particularly effective in patients with advanced myxoid liposarcoma. In addition, ...
In neighbouring Philippines, President Duterte's brutal crackdown on drugs has directly resulted in the extrajudicial executions of tens of thousands of people since June 2016 and is propelling the reintroduction of the death penalty for drug offences, which featured prominently in his election campaign...
1991, Quezon City, Philippines: Health Action Information Network Google Scholar Cockcroft A, Andersson N, Milne D, Mokoena T, Masisi M: Community views about routine HIV testing and antiretroviral treatment in Botswana: signs of progress from a cross sectional study. BMC Int Health Hum Rights...
(such as India, Bangladesh, Pakistan, Philippines, Egypt, Sudan and Ethiopia)31,33,34. Kuwait has a low (~ 24 cases per 100 000 population) incidence of TB and a low (~ 1.1%) incidence of MDR-TB31,35. Nearly 85% of all TB cases and > 90% of MDR-TB cases occur in ...
Determination of preservative and antimicrobial compounds in fish from Manila Bay, Philippines using ultra high performance liquid chromatography tandem mass spectrometry, and assessment of human dietary exposure J. Hazard. Mater., 192 (3) (2011), pp. 1739-1745 View PDFView articleView in ScopusGoog...
[13]; and the other with the Mitsubishi Tanabe Pharma Corporation to develop and commercialize inebilizumab for NMOSD (and other potential indications) in Japan and eight additional Asian countries (South Korea, Taiwan, Singapore, Indonesia, Thailand, Malaysia, the Philippines and Vietnam) [6, ...
ArticlePubMedCASGoogle Scholar Arlin Z, Case Jr DC, Moore J, Wiernik P, Feldman E, et al. Randomized multicenter trial of cytosine arabinoside with mitoxantrone or daunorubicin in previously untreated adult patients with acute nonlymphocytic leukemia (ANLL). Leukemia 4: 177–183, 1990 ...
Theta variant (P.3) is also called GR/102K.V1, which was first detected in the Philippines and then in Japan on February 2021. This variant carries 3 spike mutations, Δ141-143del, N501Y, and P681H, and is classified as the VOI by the CDC and WHO due to its lower threat than ...
“International drug control agencies need to make clear to Philippines’ President Roderigo Duterte that the surge in killings of suspected drug dealers and users is not acceptable ‘crime control,’ but instead a government failure to protect people’s most fundamental human rights,” said Phelim ...