Analgesic Drugs and Kidney Disease AN increased incidence of chronic interstitial nephritis, often associated with necrosis of the renal papillae, was noted in Switzerland by Zollinger and Spühler1during the decade 1940–1950. In their search for a cause for the sharp ri... None - 《New England...
Nonsteroidal antiiflammatory drugs can induce two different forms of acute renal failure. Decreased prostaglandin synthesis can lead to reversible renal ischemia and hemodynamically-mediated acute renal failure. Second form of acute renal failure is acute interstitial nephritis. This type of interstitial ...
it has since become clear that a substantial percentage of patients reach end-stage kidney failure over the years. Several therapeutic attempts have been proposed, with systemic steroids
Buspirone is metabolized by the liver and excreted by the kidney, and should be used with care in patients with hepatic or renal disease. The drug is classified as schedule B during pregnancy, but should not be taken during breastfeeding. Its use in children under the age of 18 years has...
Nephritis with Renal Dysfunction Grade 2 or 3 increased blood creatinine Withhold† Grade 4 increased blood creatinine Permanently discontinue Exfoliative Dermatologic Conditions Suspected SJS, TEN, or DRESS Withhold† Confirmed SJS, TEN, or DRESS Permanently discontinue Myocarditis Grade 2, 3, or 4 ...
Renal physiology of the prostaglandins and the effects of nonsteroidal anti-inflammatory agents on the kidney. American Journal of Nephrology 7: 408–418, ... WILLIAM,R,ADAM - 《Nephrology》 被引量: 12发表: 2011年 Drug-induced acute interstitial nephritis: A clinicopathological study and comparati...
improvements in the frequency and consistency of stools, whereas mineral and olive oils improved scores in 5 of the 6 total constipation symptoms. Diabetic nephropathy, hypertensive nephrosclerosis, glomerulonephritis, and polycystic kidney disease were the main etiologies that led to chronic kidney ...
Nephritis and development of drugs useful in the treatment and / or prevention of kidney dysfunction such as renal failure. The general formula (1) Wherein, R is and R a hydrogen atom, represents a chlorine atom or a nitro group which may be the same or different and R a hydrogen atom...
If kidney function alone is impaired, biliary elimination of ceftriaxone is increased; if liver function alone is impaired, renal elimination is increased. In meningitis patients, administration of 50 mg per kg bodymass leads within 2-24 hours to cerebro spinal fluid concentrations several ti...
A precise numerical designation of the incidence of renal functional disorders induced by nonsteroidal anti-inflammatory drugs (NSAID) is difficult. This is in view of the heterogeneity of the populations who consume these agents and the variability in s