Alzheimer's disease (AD) is the leading cause of dementia, presenting a significant unmet medical need worldwide. The pathogenesis of AD involves various pathophysiological events, including the accumulation of amyloid and tau, neuro-inflammation, and ne
Alzheimer's disease, the commonest cause of dementia in older people, affects 4% of the over 65s and 20% of the over 80s, 1 2 with around 400 000 sufferers in the United Kingdom.2 The prevalence of the condition will double over the next 50 years. As well as causing immense distre...
Dementia is a very common condition and, with ageing populations, will only increase in importance in the coming years. Early diagnosis and treatment help people with dementia stay independent and living at home for longer. Cholinesterase inhibitor ('anti‐dementia') drugs are used to treat people...
Alzheimer's disease (AD) is the most commonly occurring dementia and consists of both cognitive impairment and behavioral disturbances. Two types of medication classes are approved by the regulatory agencies for AD treatment. The cholinesterase inhibitors (ChEIs) are used for patients with mild, ...
The percentages generally were even higher among women, non-Hispanic white patients, people in their late 60s and early 70s, and people with low incomes. The study is published in the journalJAMAand based on data from 737,839 people with dementia, and is the first large-scale study of pres...
Alzheimer’s DiseaseIncurable, degenerative, and terminal disease The most common form of dementia痴呆SymptomsEarly stages: memory loss, Advances: confusion, irritability and aggression, mood swings, language breakdown, long-term memory loss ?Alzheimer's disease is characterised by loss of neurons and ...
The British Association for Psychopharmacology (BAP) held its summer meeting in Harrogate in July. Medical writer, John Donoghue, reports on the highlights of some of the sessions, covering cognitive dysfunction in mood disorders, early intervention in schizophrenia and management of bipolar disorder. ...
Organic mental disorders caused by HIV: update on early diagnosis and treatment. HIV directly affects the CNS, primarily causing subcortical neuropathology. Dementia as the initial presentation is rare, but organic mental changes that m... SW Perry - 《American Journal of Psychiatry》 被引量: 218...
For urge incontinence: Timed or prompted voiding; bedtime fluid/caffeine restriction; darifenacin (Enablex) 9 For BPH: 5-alpha-reductase inhibitor (finasteride [Proscar], dutasteride [Avodart]) 6 Urinary incontinence is common in patients with dementia and can be a side effect of the ...
(CPB) in the 1950s and leads to increased length of hospital stay, costs, risk of dementia, and mortality. Mechanisms involved include acute inflammation and decreased serotonin levels. A double-blind, randomized, placebo-controlled trial enrolled 61 adult Iranians who were candidates for coronary...